Alcohol Use Research Study
Researchers at the Medical University of South Carolina are conducting a study investigating memory problems and alcohol use in older adults.
Fast Facts
Ages 60-85
Regularly Engage in Heavy Alcohol Consumption
Compensation May Be Provided
Conducted in Charleston, SC
Study Background
Researchers at the Medical University of South Carolina are conducting a study investigating memory problems and alcohol use in older adults.
This study aims to test a brain stimulation technique called theta burst stimulation (TBS) to see how it affects heavy drinking and memory problems. TBS uses magnetic pulses to stimulate specific brain areas without surgery or anesthesia. Researchers focus on a part of the brain linked to reducing alcohol use and improving memory and thinking.
Participants will undergo brain imaging, memory tests, and interviews about their drinking habits. The treatment involves 5 days of rTMS given in a single day, approved by the FDA for depression. Researchers are exploring if this method can enhance memory, thinking, and mood while reducing alcohol use. This study will measure changes in cognitive function, drinking habits, and brain networks related to memory and craving.
Study Background
Researchers at the Medical University of South Carolina are conducting a study investigating memory problems and alcohol use in older adults.
This study aims to test a brain stimulation technique called theta burst stimulation (TBS) to see how it affects heavy drinking and memory problems. TBS uses magnetic pulses to stimulate specific brain areas without surgery or anesthesia. Researchers focus on a part of the brain linked to reducing alcohol use and improving memory and thinking.
Participants will undergo brain imaging, memory tests, and interviews about their drinking habits. The treatment involves 5 days of rTMS given in a single day, approved by the FDA for depression. Researchers are exploring if this method can enhance memory, thinking, and mood while reducing alcohol use. This study will measure changes in cognitive function, drinking habits, and brain networks related to memory and craving.
Additional Information
The purpose of this study is to examine how brain stimulation techniques affect heavy drinking and memory problems in older adults.
Participants may qualify for this study if they meet the following criteria.
Inclusion Criteria:
- Ages 60-85
- Regularly engage in heavy alcohol consumption
- Experiencing mild cognitive impairment (e.g., forgetfulness, difficulty problem-solving or finding the right words)
- Heavily consumed alcohol at least 4 days in the last month
- Able to undergo MRI
- Speak English
Exclusion Criteria
- Current substance use disorder other than alcohol or nicotine
- Have received investigational medications or devices in the last 30 days
- Taking medications that affect cognitive function (e.g., sedatives, anticholinergics)
- Major or unstable medical conditions
- Diagnosed with psychiatric conditions (e.g., Bipolar disorder, schizophrenia, or related conditions)
- Diagnosed with dementia
- Major visual or auditory difficulties
- Pregnant
Once enrolled, you will participate in various visits including clinic and treatment visits, assessments, completion of questionnaires, and final assessments, as outlined below:
Clinic Visit: You’ll visit the clinic for a check-up where we’ll take blood and urine samples, ask questions about your health and habits, and test your memory and thinking skills.
Treatment Phase: You’ll start the treatment phase, lasting five days within a week. Each treatment day involves about three hours of theta burst stimulation (TBS). We’ll also collect urine samples and ask more questions during this time.
Post-Treatment Assessments: After completing the treatment, you’ll have additional assessments, including brain imaging and more questions about your behavior and memory skills.
Follow-up Questionnaires: Over the following weeks, you’ll receive online questionnaires to fill out.
Final Assessments: At the end of the study, we’ll repeat some assessments to see if there are any changes.
Compensation is provided up to $500 for your participation.
There is no cost for you to participate in our research study.
