This study is being conducted to evaluate whether an investigational medication may safely improve sperm count, testosterone levels, and symptoms associated with low testosterone in men with reduced fertility.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Men ages 18-49
• Have low testosterone and sperm count
• Not currently using testosterone therapy or fertility/hormone medications
• Willing to provide blood and semen samples

If you qualify and choose to participate, you will first complete a phone screening interview to determine initial eligibility. Qualified participants will attend approximately 7 in-person clinic visits, 3–4 separate semen lab visits, and 1 follow-up phone call over about 28 weeks.

During the study, participants will:

• Take a once-weekly oral study capsule at home for 16 weeks
• Provide blood and semen samples
• Complete health assessments and physical exams
• Undergo laboratory testing, including hormone and fertility evaluations
• Meet with study staff for ongoing monitoring throughout participation
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Participants may receive compensation up to $4,500 for time and study-related participation.

Participants may also receive:

• Study-related medical evaluations and monitoring by a study physician
• Blood tests and laboratory work, including hormone and general health panels
• Semen analysis and fertility-related assessments
• Physical exams and specialized testing, such as ECGs and urological evaluations
• Health insights that may identify previously unknown conditions

There is no cost for you to participate in our research study.