Progestin Contraception Research Study
Researchers at Oregon Health and Science University Women's Health research Unit want to learn more about menstrual changes in progestin contraception users. This study aims to discover what changes in the endometrium lead to different bleeding patterns during the first year of progestin contraception use.
Fast Facts
Regular Menstrual Periods
not currently using hormonal contraceptives or gender-affirming hormonal treatment
Females 18-40 years old
Compensation Provided
Conducted in Portland, Oregon
Study Background
This study investigates why some people who use progestin-only contraception, such as the contraceptive implant (Nexplanon) or contraceptive injectable (Depo-Provera), have changes to their menstrual bleeding patterns.
As part of this study, you will receive your choice of the contraceptive implant or contraceptive injectable. Participation will last up to 13 months and will involve 5 or 6 visits to our clinic at OHSU as well as 8 or 9 monthly phone call or email check-ins. You will be asked to allow us to collect a tissue sample from the lining of your uterus (endometrial biopsy) at 4-time points over the course of 12 months.
Study Background
This study investigates why some people who use progestin-only contraception, such as the contraceptive implant (Nexplanon) or contraceptive injectable (Depo-Provera), have changes to their menstrual bleeding patterns.
As part of this study, you will receive your choice of the contraceptive implant or contraceptive injectable. Participation will last up to 13 months and will involve 5 or 6 visits to our clinic at OHSU as well as 8 or 9 monthly phone call or email check-ins. You will be asked to allow us to collect a tissue sample from the lining of your uterus (endometrial biopsy) at 4-time points over the course of 12 months.
Additional Information
You may qualify for this study if you meet the following criteria.
Key Criteria:
18-40 years old
Regular menstrual periods
- Not currently using hormonal contraceptives or gender-affirming hormonal treatment
Not currently using an intrauterine device or intrauterine system (IUD or IUS)
Seeking the contraceptive implant (Nexplanon) or contraceptive injectable (Depo-Provera)
Not currently pregnant or planning pregnancy during the study
- Spanish-speakers are encouraged to participate
If eligible, participation involves:
- Your participation in the study will consist of 5 or 6 visits over 13 months. Visits will last up to 60 minutes.
- You will be asked to allow us to collect a tissue sample from the lining of your uterus (endometrial biopsy) at 4 time points over the course of 12 months.
