Researchers at Johns Hopkins University School of Medicine want to understand how people feel and behave when they stop using e-cigarettes, including the nicotine dependence and withdrawal symptoms related to stopping vaping. Findings will help inform future treatment for people who want to reduce or quit e-cigarette use.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Ages 21-55
• Daily e-cigarette user interested in reducing or quitting
• No regular use of other tobacco products (e.g., traditional cigarettes, cigars, hookah)

Overall Duration

• Participation involves a screening visit, a 7-day inpatient stay, and a follow-up visit

Screening Visit

• About 3-4 hours to determine eligibility

7-Day Residential Stay

• An overnight stay at the Johns Hopkins Bayview Medical Center
• Participants do not use e-cigarettes during this period
• Random assignment to a nicotine patch, a placebo patch, or no patch
• Questionnaires and computer tasks about four times per day
• Wear a wrist-watch and headband that record sleep
• A daily urine sample

Follow-Up Visit

• About 1-2 hours, one week after the residential stay
• Questionnaires, computer tasks, and a urine sample

Other Details

• Transportation for the residential stay is provided

Participants may receive up to $2,275 for completing the study.

There is no cost for you to participate in our research study.