The EXPLORE Study is being done to help researchers understand how the development of learning and decision-making is related to eating behaviors in adolescence.

You or your child may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Girls ages 12-17
• At least 6 times in the past 3 months, experienced binge eating, food restriction, skipping meals, or overeating
• Have had first menstrual period
• Concerned with weight or body image
• Able to undergo an MRI (no non-removable metal in the body or claustrophobia)
• Have a parent or caregiver who is able to consent to study participation and attend the fMRI visit

Exclusion Criteria:

• Serious medical conditions (e.g., diabetes, brain injury, cancer)
• Current or past diagnosis of bipolar disorder, substance use disorder, autism spectrum disorder, psychosis, or mania
• Previous anorexia nervosa diagnosis
• Pregnant or planning to become pregnant

Visit 1: Screening (In-Person or Virtual)

• Complete interviews and questionnaires about your eating and your mental and physical health
• Have your height and blind weight measured (meaning you will not see your numerical weight)
• This visit takes 2-3 hours and can be done at the VCU Jackson Center, the VCU CARI Center, or virtually

Medical Screening

• Eligible participants complete a free 30-minute medical screening with a nurse practitioner
• Includes a review of medical history, vital sign measurements, and a blood draw

Visit 2: MRI Scan (In-Person)

• Takes place at the VCU CARI Center and takes about 2 hours
• Complete a decision-making task during a 1-hour MRI brain scan, then a brief computer task outside the scanner
• A parent or caregiver must be present for the consent process and the fMRI visit

Annual Follow-Ups (2 Years)

• Complete follow-ups 1 and 2 years after Visit 2, in person or remotely
• Each follow-up includes brief interview questions and two decision-making computer games

Participants can receive up to $240 over time, plus up to $150 in bonuses, for a total of up to $390. Perks include a free standardized breakfast or snack, free blood work with results available upon request to share with your medical provider, and a free consultation with a study nurse practitioner. Transportation is not provided.

There is no cost for you/your teen to participate in our research study.