Smoking Research Study

Researchers at the University of Oklahoma Health Sciences Center and Oklahoma State University Center for Health Sciences want to find better treatments for smokers.

Fast Facts

Ages 21-65

Smoke Cigarettes Daily

Compensation Provided

Conducted in
Tulsa, OK

Study Background

Help us learn more about whether a medication has the potential to affect smoking behavior.

Each year, smoking causes over 480,000 deaths in the United States and over 7 million deaths worldwide. Unfortunately, even with the best treatments currently available, nearly 2 out of 3 smokers who quit will return to smoking within six months. Many relapses occur when smokers are exposed to people, settings, or other cues that remind them of smoking and produce strong urges to smoke.

Our researchers are studying whether a medication has the potential to affect smoking behavior by reducing the cravings that occur in response to smoking cues. This medication is approved by the Food and Drug Administration (FDA) and is widely used to treat high blood pressure and other related problems, but is not yet approved to treat smoking.

Participating in this study may contribute valuable information that can help those who want to quit smoking in the future. Further research on smoking treatments and join our compensated study today!

Study Background

Help us learn more about whether a medication has the potential to affect smoking behavior.

Each year, smoking causes over 480,000 deaths in the United States and over 7 million deaths worldwide. Unfortunately, even with the best treatments currently available, nearly 2 out of 3 smokers who quit will return to smoking within six months. Many relapses occur when smokers are exposed to people, settings, or other cues that remind them of smoking and produce strong urges to smoke.

Our researchers are studying whether a medication has the potential to affect smoking behavior by reducing the cravings that occur in response to smoking cues. This medication is approved by the Food and Drug Administration (FDA) and is widely used to treat high blood pressure and other related problems, but is not yet approved to treat smoking.

Participating in this study may contribute valuable information that can help those who want to quit smoking in the future. Further research on smoking treatments and join our compensated study today!

Additional Information

We are studying whether a medication has the potential to affect smoking behavior. This medication is approved by the FDA and is widely used to treat high blood pressure and other related problems, but is not yet approved to treat smoking.

You may qualify for this study if you meet the following criteria.

Inclusion Criteria:

  • Ages 21-65
  • Smoke cigarettes daily
  • Not receiving treatment to quit smoking
  • Not planning to quit smoking in the next 60 days
  • Have been smoking regularly for at least 1 year
  • No personal history of heart disease, asthma, diabetes (insulin-dependent), seizures or head trauma
  • Able to undergo an MRI (no non-removable metal on or in your body)
  • In generally good health
  • Right-handed or Ambidextrous

Participants will attend one remote visit to complete consent and baseline questionnaires that will take around 2 hours. Eligible participants will then attend a detailed medical screening visit in-person at the center to determine final eligibility that will also take around 2 hours.

Those determined eligible to safely complete the study will attend 4 MRI visits where they will take different combinations of FDA-approved medications prior to each MRI. These visits will be 4-5 hours in length.

Compensation up to $1,000 is provided for your time.

There is no cost for you to participate in our research study.