Opioid Use Disorder Research Study
Researchers at Stony Brook University Department of Psychiatry are conducting a study to learn more about how individuals with opioid use disorder respond to stress.
Fast Facts
Ages 18-55
Diagnosed With Opioid Use Disorder
Compensation Provided
Conducted in
Stony Brook, NY
Study Background
Researchers want to better understand the relationship between psychosocial stress and future drug use in individuals with opioid use disorder (OUD).
Previous research shows that stress plays a large part in how successful individuals are in managing addiction, but we have yet to understand why. Through this study, we hope to better understand how individuals with OUD respond to stress.
We predict that addiction may change the way the brain responds to stress, making certain individuals more likely to experience continued drug use and relapse. We hope that the results of this study will allow researchers to improve treatments for OUD in the future.
Study Background
Researchers want to better understand the relationship between psychosocial stress and future drug use in individuals with opioid use disorder (OUD).
Previous research shows that stress plays a large part in how successful individuals are in managing addiction, but we have yet to understand why. Through this study, we hope to better understand how individuals with OUD respond to stress.
We predict that addiction may change the way the brain responds to stress, making certain individuals more likely to experience continued drug use and relapse. We hope that the results of this study will allow researchers to improve treatments for OUD in the future.
Additional Information
The purpose of this study is to better understand the relationship between psychosocial stress and future drug use in individuals with OUD.
You may qualify for this study if you meet the following criteria.
Inclusion Criteria:
- Ages 18-55
- Diagnosed with opioid use disorder (OUD)
- Taking medication-assisted treatment for OUD (e.g., buprenorphine, methadone)
- No major medical, psychiatric, or neurological illness interfering with daily activities
- Fluent in English
- If female, not pregnant or breastfeeding
- Not receiving in-patient drug treatment required by a court or judge
- Able to undergo MRI scan (no metal in the body, no claustrophobia)
This study will last approximately 8 months and will include several in-person visits to Stony Brook University Medical Center located in Stony Brook, NY. Please note that this study does not directly treat OUD. The goal of this study is to conduct research to improve and develop long-term treatment options.
During the first several days, participants will complete the in-person components of this study including questionnaires, clinical interviews, MRI scans, and laboratory tests. After the initial assessments, participants will receive a call once per month over the next 8 months to answer questions about treatment and sobriety.
Over the course of this study, participants may be asked to complete:
- Surveys and questionnaires
- Medical physical exam, including routine blood draw
- Confidential clinical interviews
- Cognitive and laboratory testing, including during mildly stressful situations
- One or more MRI scans of your brain
- Computer tasks, including during MRI
- Confidential urine screenings
- Monthly phone calls with the research team
In total, you have the opportunity to earn up to $510 for participation in this study.
There is no cost for you to participate in our research study.