Nexplanon Research Study
Researchers at Oregon Health & Science University are studying a medication that may help reduce contraceptive-related bleeding side effects.
Fast Facts
Women Ages 15-45 Currently Using Nexplanon
Experience Implant Related Bleeding
Compensation Provided
Conducted in Portland, OR
Study Background
Are you bothered by frequent or persistent bleeding with the contraceptive implant?
The Women’s Health Research Unit is conducting a study to determine if a medication called Tranexamic Acid (TXA) can help reduce irregular menstrual bleeding in people who use the contraceptive implant (Nexplanon).
Participants will attend three visits to OHSU, and will keep a daily record of their bleeding. Participants may take the study drug or placebo for 5 days.
Join our compensated study!
Study Background
Are you bothered by frequent or persistent bleeding with the contraceptive implant?
The Women’s Health Research Unit is conducting a study to determine if a medication called Tranexamic Acid (TXA) can help reduce irregular menstrual bleeding in people who use the contraceptive implant (Nexplanon).
Participants will attend three visits to OHSU, and will keep a daily record of their bleeding. Participants may take the study drug or placebo for 5 days.
Join our compensated study!
Additional Information
The purpose of this study is to learn if an FDA approved drug called “Tranexamic acid” or “TXA” can help with the bothersome
bleeding or spotting that many users of the contraceptive implant “Nexplanon” experience.
You may qualify for this study if you meet the following criteria.
Inclusion Criteria:
- Women ages 15-45
- Currently using Nexplanon
- Experience frequent or persistent bleeding while using implant
- If female- not currently pregnant, breastfeeding, or planning to become pregnant
- Have no history of bleeding disorder
- Do not use cannabis or smoke cigarettes regularly
- Do not use any anti-coagulants (blood-thinners)
- No history of breast or uterine cancer
- No history of bleeding disorders, blood clots, or clotting disorders
- Have never become pregnant with Nexplanon
- Have not had a baby in the last 6 months
- Have not had a miscarriage or abortion in the past 6 weeks
- Implant was not placed in the last month and is not due to be taken out for at least 2 months
Once enrolled, this study involves:
- Participating in a Screening Visit (estimated 1 hour)
- Provide basic demographic, health, and behavioral information
- Undergo a physical exam
- Attending an Enrollment Visit (estimated 30 minutes)
- Complete a pregnancy test
- Start the study drug (or placebo) if experiencing an active bleeding episode
- Track bleeding via text message bleeding diary
- Completing the End of Study Visit (estimated 30 minutes)
- Provide vital signs
- Review bleeding diary, medications, health changes
- Complete satisfaction questionnaire
Compensation is provided up to $425 for your participation.
There is no cost for you to participate in our research study.
