Hemophilia A Research Study
Researchers at Oregon Health & Science University are studying why Hemophilia A carriers’ bleeding symptoms don’t always match their blood factor levels, using menstrual blood samples, surveys, a diary, and a blood draw.
Fast Facts
Menstruating Individuals Ages 18-45
Carrier of Hemophilia A
Compensation Provided
Conducted In Portland, OR
Study Background
CHARM: Carriers of Hemophilia A Reporting on Menstruation
Hemophilia A is a genetic condition that affects blood clotting, making individuals more prone to excessive bleeding. Carriers of Hemophilia A, often menstruating individuals, may experience unusual bleeding symptoms that don’t always match the levels of a specific blood protein called factor 8, which is essential for clotting. This inconsistency makes it challenging for doctors to understand and manage their symptoms effectively.
Researchers at Oregon Health & Science University are working to bridge this gap by collecting data from participants who are carriers of Hemophilia A. The study involves gathering menstrual blood samples using a provided menstrual cup, completing two surveys and a bleeding diary, and participating in one blood draw. By analyzing this information, researchers hope to gain insights that could improve diagnosis and treatment options for carriers, ultimately leading to better care and quality of life.
Study Background
CHARM: Carriers of Hemophilia A Reporting on Menstruation
Hemophilia A is a genetic condition that affects blood clotting, making individuals more prone to excessive bleeding. Carriers of Hemophilia A, often menstruating individuals, may experience unusual bleeding symptoms that don’t always match the levels of a specific blood protein called factor 8, which is essential for clotting. This inconsistency makes it challenging for doctors to understand and manage their symptoms effectively.
Researchers at Oregon Health & Science University are working to bridge this gap by collecting data from participants who are carriers of Hemophilia A. The study involves gathering menstrual blood samples using a provided menstrual cup, completing two surveys and a bleeding diary, and participating in one blood draw. By analyzing this information, researchers hope to gain insights that could improve diagnosis and treatment options for carriers, ultimately leading to better care and quality of life.
Additional Information
This study is being done to understand why carriers of Hemophilia A often experience bleeding symptoms that don’t match their levels of factor 8, a protein crucial for blood clotting. By collecting menstrual blood samples, survey responses, a bleeding diary, and blood draw data, researchers aim to uncover patterns that can improve diagnosis and treatment, ultimately leading to better care for carriers of this condition.
You may qualify for this survey if you meet the following criteria.
Inclusion Criteria:
- Menstruating individuals ages 18-45
- Carrier of Hemophilia A
- Having regular menstrual cycles
- Do not have an IUD
- No other inherited or acquired bleeding disorders or current anticoagulant/antiplatelet use
- If prescribed NSAIDS and or antifibrinolytics, able to stop taking them
- Able to attend in person visits at an OHSU clinic
If you participate in this study, here’s what to expect:
Screening and Enrollment Visit (90 minutes)
Meet with the study team at an OHSU clinic.
Review your medical history and receive all study materials.
First Sample Drop-Off During Your Period (30 minutes)
Drop off your first sample.
Complete a blood draw during this visit.
Additional Sample Drop-Offs (10 minutes each)
Return to the clinic for quick drop-offs of the remaining samples during your period.
All visits are in person at an OHSU clinic and scheduled to fit the timing of your menstrual cycle.
Yes, you will be paid for participating in this study. The total compensation is approximately $245, which includes:
$25 for completing the surveys and diary.
$25 for the blood draw.
$40 for each day of sample collection.
$75 as a bonus for completing all sample drop-offs.
Payment is based on your participation in each part of the study.
There is no cost for you to participate in our research study.