Opioid Use Disorder Research Study
Researchers at Yale University are conducting a study on brain activity and opioid abstinence for individuals currently receiving methadone or buprenorphine treatment.
Fast Facts
In Treatment (e.g., Buprenorphine, Methadone) For Opioid Use Through A Program Or Clinic
18-50
Years Old
Compensation
Provided
Conducted in
New Haven, CT
Study Background
This study explores how brain connectivity relates to opioid relapse during treatment.
Understanding how the brain functions during opioid use disorder (OUD) treatment can offer valuable insight into the mechanisms of relapse. This study uses fMRI scans, surveys, and computer-based tasks to investigate functional brain patterns in individuals receiving medication-assisted treatment (MAT) such as methadone or buprenorphine.
By identifying patterns of brain activity that may predict relapse, researchers aim to support the development of more effective, evidence-based interventions for OUD. Participation is confidential, and findings will contribute to improving long-term outcomes for those in recovery.
Study Background
This study explores how brain connectivity relates to opioid relapse during treatment.
Understanding how the brain functions during opioid use disorder (OUD) treatment can offer valuable insight into the mechanisms of relapse. This study uses fMRI scans, surveys, and computer-based tasks to investigate functional brain patterns in individuals receiving medication-assisted treatment (MAT) such as methadone or buprenorphine.
By identifying patterns of brain activity that may predict relapse, researchers aim to support the development of more effective, evidence-based interventions for OUD. Participation is confidential, and findings will contribute to improving long-term outcomes for those in recovery.
Additional Information
The study is being conducted to understand how brain activity and decision-making processes are linked to relapse in people undergoing treatment for opioid use disorder.
You may be eligible for this study if you meet the following criteria.
Inclusion Criteria:
- In treatment (e.g., buprenorphine, methadone) for opioid use through a program or clinic
- Recent initiation of methadone or buprenorphine within the past year
- Ages 18-50
You will complete in-person sessions involving surveys, an fMRI brain scan, and computer tasks. You’ll also be asked to complete short monthly follow-ups (in-person or by phone) for 6 months after the main study.
You can receive up to $680 total, including:
$50 for screening
$250 for the fMRI session
$100 for the phenotyping session
$180 for monthly follow-ups ($30 × 6)
Up to $66 additional for completing a decision-making task
Transportation support of up to $25 each way per visit (Uber, bus, gas reimbursement, etc.)
There is no cost for you to participate in our research study.