Schizophrenia Research Study

Researchers at Arch Clinical Trials are studying a drug to help with thinking problems in adults with schizophrenia.

Fast Facts

Diagnosed With Schizophrenia

Receiving Antipsychotic Medication Other Than Clozapine or Cobenfy

Compensation

Provided

Conducted in

St. Louis, MO & Willing to Remain Inpatient (Stay in The Hospital) For up to 4.5 Weeks

Study Background

This study is looking at whether a study drug can improve memory, attention, and other thinking skills when added to your current antipsychotic medicine.

Some adults with schizophrenia have trouble with memory, focus, and problem-solving. A study drug is being tested as a new treatment to see if it can help with these issues.

If you join, you will keep taking your current antipsychotic medicine. You may receive either the study drug or a placebo. Neither you nor your doctors will know which one you get. The study starts with two short outpatient visits for screening, followed by a 32-day stay at the clinic, and ends with a safety follow-up visit

Study Background

This study is looking at whether a study drug can improve memory, attention, and other thinking skills when added to your current antipsychotic medicine.

Some adults with schizophrenia have trouble with memory, focus, and problem-solving. A study drug is being tested as a new treatment to see if it can help with these issues.

If you join, you will keep taking your current antipsychotic medicine. You may receive either the study drug or a placebo. Neither you nor your doctors will know which one you get. The study starts with two short outpatient visits for screening, followed by a 32-day stay at the clinic, and ends with a safety follow-up visit.

Additional Information

The study wants to see if a study drug is safe and can improve thinking problems in adults with schizophrenia.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

  • Diagnosed with schizophrenia
  • Receiving antipsychotic medication other than clozapine or Cobenfy
  • Willing to remain inpatient (stay in the hospital) for up to 4.5 weeks
  • Ages 18-55
  • BMI between 18 and 40

Exclusion Criteria:

  • Use substances such as cocaine, methamphetamine, or cannabis
  • Suicidal ideation
  • History of epilepsy
  • Pregnant, breastfeeding, or planning to become pregnant in the near future
  • Two outpatient visits for screening.

  • Up to 32 days staying at the clinic.

  • Labs, vitals, EKGs, physical exams, and questionnaires during the stay.

  • One follow-up visit to check safety.

You will be paid for participating in this research study up to $300 for completing the initial evaluation period. If you live within 55 miles, Lyft rides are available. You will also get 3 meals per day, coffee, and your blood work results if you want them.

There is no cost for you to participate in our research study.