Brain Imaging Research Study

Researchers at Yale University are conducting a study on brain function for adults without psychiatric or major neurological conditions.

Fast Facts

Have not been diagnosed with a psychiatric disorder or a major neurological condition

18-70

Years Old

Compensation

Provided

Conducted in

New Haven, CT

Study Background

Advancing Brain Research Through Imaging

The Yale Department of Psychiatry is leading a research study to better understand how brain activity differs in individuals without psychiatric or neurological diagnoses. This work builds on decades of innovation at the Yale OCD Research Clinic and is supported by the NIH and other leading institutions.

Participants will complete a brief screening and intake process before attending 2–4 study visits in New Haven, CT. These visits may include MRI and PET scans, cognitive tasks, and non-invasive brain stimulation. Compensation is provided, and some studies offer free medical screening or bloodwork. Your participation helps researchers uncover new insights that could lead to safer, more effective treatments for OCD and related conditions.

HIC #2000039024

Study Background

Advancing Brain Research Through Imaging

The Yale Department of Psychiatry is leading a research study to better understand how brain activity differs in individuals without psychiatric or neurological diagnoses. This work builds on decades of innovation at the Yale OCD Research Clinic and is supported by the NIH and other leading institutions.

Participants will complete a brief screening and intake process before attending 2–4 study visits in New Haven, CT. These visits may include MRI and PET scans, cognitive tasks, and non-invasive brain stimulation. Compensation is provided, and some studies offer free medical screening or bloodwork. Your participation helps researchers uncover new insights that could lead to safer, more effective treatments for OCD and related conditions.

HIC #2000039024

Additional Information

This study is being conducted to better understand how the brain functions in individuals who have not been diagnosed with psychiatric or major neurological conditions. By using advanced brain imaging techniques—such as MRI and PET scans—researchers aim to establish a clearer picture of typical brain activity. This foundational knowledge helps scientists identify how brain function may differ in individuals with conditions like OCD, ultimately contributing to the development of more effective and targeted treatments.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:
  • Ages 18-70
  • Able to speak/read English fluently
  • Have never been diagnosed with a psychiatric disorder (such as depression, anxiety, schizophrenia)
  • Have no major neurological conditions (such as epilepsy, Parkinson’s disease, or multiple sclerosis)
  • Are willing and able to attend study visits in New Haven, CT 
Exclusion Criteria:
  • Current or previous psychiatric disorder diagnosed by a health professional
  • Currently taking psychiatric medication
  • History of head injury with loss of consciousness for more than 30 minutes.
  • Major neurological conditions (e.g., epilepsy, Parkinson’s, etc.)
  • Current suicidal intent or plan

Once they complete the baseline screening (via phone) and intake (virtual/zoom), participants will be enrolled in main study procedures, which may include MRI scanning, PET scanning, written assessments, cognitive tasks, and brain stimulation. These typically involve 2-4 visits total. Some participants may be enrolled in a study involving psychiatric medication, which takes place over 16 weeks. 

Participants may receive different compensation amounts depending on the study they join.

There is no cost for you to participate in our research study.