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Vaping & Smoking
Research Study

People are increasingly using e-cigarettes, especially those with cooling flavors, but we don’t fully understand how these flavors affect user experience or potential for addiction. This is important because flavoring may influence how appealing and habit-forming e-cigarettes are. This study will examine how adults respond to different cooling flavors in nicotine e-cigarettes, including how they feel, how much they like them, and their effects on the body.

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Fast Facts

Smoke cigarettes regularly

Use e-cigarettes/vapes regularly

Compensation
up to $510

Conducted in
New Haven, CT

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Additional Information

This study is being conducted to better understand how cooling flavors in e-cigarettes affect people and to explore ways to improve knowledge about their impact on health, user experience, and potential for addiction.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

  • 18 years of age or older
  • Regular use of cigarettes
  • Regular use of e-cigarettes (vaping)
  • Not currently trying to quit nicotine or tobacco use
  • Able to read and speak English

 

Exclusion Criteria:

  • Current use of illegal drugs (excluding cannabis)
  • Pregnant, trying to become pregnant, or breastfeeding
  • Known allergies to e-liquid ingredients
  • Not medically stable

Overall Duration
This study includes one intake visit, three lab visits, and two follow-up phone calls over about 6 months.

In-Lab Activities
Participants will complete a total of four in-person visits in the New Haven area. The first visit (about 2 hours) is an intake visit to see if you are eligible. During this visit, you will provide a urine sample, review your medical and nicotine use history, and complete health questionnaires.

If eligible, you will attend three lab visits, each lasting about 4–5 hours. During each visit, you will try six different nicotine e-liquids that may have cooling flavors. After each sample, you will answer questions about how you feel and what you think of the product. Researchers will also collect saliva samples and measure your blood pressure, heart rate, and oxygen levels. There will be short breaks between each sample. At the end of each visit, you will have time to use any of the e-liquids again.

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Participants can receive compensation for their time, with the opportunity to earn up to $510 for completing all parts of the study. Participants will also receive payment after each lab visit. Transportation support or rideshare services may be available after the first visit if needed.

There is no cost for you to participate in our research study.

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