This study is being done to learn whether the sleep medication Suvorexant can help adults who are taking medication for opioid use disorder and are struggling with insomnia. Researchers want to understand if improving sleep can also support overall health and recovery.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Age 18–70

• Taking buprenorphine or methadone for opioid use disorder

• Experiencing trouble sleeping

• Able to attend in-person study visits

Exclusion Criteria:

• Current use of sleep medications that cannot be safely stopped for the study

• Pregnancy or breastfeeding

• Known allergy or sensitivity to Suvorexant

The study lasts about 16 weeks. During this time, you will complete several in‑person visits and at‑home sleep activities. 

•   A 30-minute screening phone call to determine initial eligibility
•   A 3-hour intake appointment including interviews, questionnaires, an ECG, and a blood draw
•   Three overnight polysomnography (PSG/sleep study) sessions
•   Up to 6 additional in-person visits
•   A brief telephone call with a study doctor

Yes. Participants who qualify and complete all parts of the study can receive up to $1,555. This payment is provided to thank you for your time and effort during the study.

There is no cost for you to participate in our research study.