This study is being done to learn whether the sleep medication Suvorexant can help adults who are taking medication for opioid use disorder and are struggling with insomnia. Researchers want to understand if improving sleep can also support overall health and recovery.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Age 18–70

• Taking buprenorphine or methadone for opioid use disorder

• Experiencing insomnia 3+ nights/week for the last 3+ months

• Able to attend in-person study visits at Butler Hospital

Exclusion Criteria:

• Current use of sleep medications that cannot be safely stopped for the study

• Untreated or unstable medical or psychiatric conditions that could affect sleep

• Pregnancy or breastfeeding

• Known allergy or sensitivity to Suvorexant

• Substance use disorders other than opioid use disorder

The study lasts about 8 weeks. During this time, you will complete several in‑person visits and at‑home sleep activities. 

•   A 30-minute screening phone call to determine initial eligibility
•   A 3-hour intake appointment including interviews, questionnaires, an ECG, and a blood draw
•   Three overnight polysomnography (PSG/sleep study) sessions at Kent Hospital
•   Up to 6 additional in-person visits at Butler Hospital
•   A brief telephone call with a study doctor

Yes. Participants who qualify and complete all parts of the study can receive up to $1,555. This payment is provided to thank you for your time and effort during the study.

There is no cost for you to participate in our research study.