Asthma Research Study
Researchers at the University of Colorado School of Medicine are conducting a study on the investigational medication CXA-10 to assess its potential in managing asthma symptoms in overweight and obese adults.
Fast Facts
Diagnosed With Asthma & Use A Daily Inhaler
Overweight or obese
(BMI > 30kg/m2)
Compensation Provided
Conducted in Denver, CO
Study Background
Researchers at the University of Colorado School of Medicine are conducting a study on the oral medication CXA-10 for managing asthma symptoms in overweight and obese adults.
This study aims to explore the effectiveness of CXA-10, an oral medication, in treating asthma symptoms in overweight or obese individuals. As part of a double-blind, randomized, placebo-controlled crossover trial, participants will receive both the investigational drug and a placebo over the course of the study. The research is designed to evaluate how CXA-10 affects asthma symptoms and whether it can provide a new treatment option for overweight or obese individuals who may not respond well to current asthma therapies. This study is one of the only studies of its kind in the country, with a specific focus on the relationship between asthma and body weight.
Participants will be required to attend 5-7 in-person visits at the University of Colorado Anschutz Medical Campus in Aurora, Colorado. These visits will involve various assessments, including breathing tests, blood work, possible bronchoscopies, and questionnaires about asthma management and lifestyle. All study-related procedures will be provided at no cost to participants, and compensation is offered for participation.
Study Background
Researchers at the University of Colorado School of Medicine are conducting a study on the oral medication CXA-10 for managing asthma symptoms in overweight and obese adults.
This study aims to explore the effectiveness of CXA-10, an oral medication, in treating asthma symptoms in overweight or obese individuals. As part of a double-blind, randomized, placebo-controlled crossover trial, participants will receive both the investigational drug and a placebo over the course of the study. The research is designed to evaluate how CXA-10 affects asthma symptoms and whether it can provide a new treatment option for overweight or obese individuals who may not respond well to current asthma therapies. This study is one of the only studies of its kind in the country, with a specific focus on the relationship between asthma and body weight.
Participants will be required to attend 5-7 in-person visits at the University of Colorado Anschutz Medical Campus in Aurora, Colorado. These visits will involve various assessments, including breathing tests, blood work, possible bronchoscopies, and questionnaires about asthma management and lifestyle. All study-related procedures will be provided at no cost to participants, and compensation is offered for participation.
Additional Information
This study is being done to determine the safety and efficacy of CXA-10 in treating asthma symptoms in overweight or obese adults.
You may qualify for this study if you meet the following criteria.
Inclusion Criteria:
- Diagnosed with asthma and use a daily inhaler
- Overweight or obese (BMI > 30kg/m2)
- No history of heart conditions
- Do not smoke cigarettes or vape
- Not pregnant, breastfeeding, or planning to get pregnant in the next 8 months
- Previous smokers can apply, but must have less than a 15 pack year history
If you decide to participate, you will:
Attend 5-7 in-person visits at the University of Colorado Anschutz Medical Campus in Aurora, Colorado
Complete breathing tests, blood work, and questionnaires about your asthma and lifestyle
Undergo possible bronchoscopy (up to 2 times) and methacholine challenge visits (up to 4 times)
Receive both the investigational drug (CXA-10) and placebo in a randomized, crossover manner
Participate in a total study duration of 18-22 weeks, with 6 weeks on placebo, 6 weeks on CXA-10, and a 4-week washout period between treatments
Have a physical exam and pulmonary function tests conducted by a pulmonologist
Yes, participants will be compensated up to $1,275 for their time and effort. You are responsible for your own transportation to and from the study visits. Additional perks include a physical exam by a pulmonologist, pulmonary function testing, and blood work at no cost.
There is no cost for you to participate in our research study.