Dengue Vaccine Research Study

Help researchers at the National Institutes of Health (NIH) better understand protection against dengue. Help make better dengue vaccines, and join our compensated study today!

Fast Facts

History of dengue infection OR lived in/traveled to a region where dengue infection is common OR never had dengue or lived in/traveled to locations where dengue infection is common

18 - 59 Years Old

Compensation Provided

Conducted in Bethesda, MD

About Our Research Study

Participate in a compensated research study that will help researchers at the NIH understand how previous dengue infection impacts vaccine responses.
 

Did you know that millions of cases of dengue infection occur worldwide each year?

Dengue fever (also called dengue hemorrhagic fever) is a mosquito-borne illness that occurs in tropical and subtropical areas of the world. A severe case of dengue fever can cause serious bleeding, a sudden drop in blood pressure, or death.

By taking part in our research study, you can help us make better dengue vaccines that may be used to prevent the virus. Join our compensated study today!

About Our Research Study

Participate in a compensated research study that will help researchers at the NIH understand how previous dengue infection impacts vaccine responses.
 
Did you know that millions of cases of dengue infection occur worldwide each year?
 
Dengue fever (also called dengue hemorrhagic fever) is a mosquito-borne illness that occurs in tropical and subtropical areas of the world. A severe case of dengue fever can cause serious bleeding, a sudden drop in blood pressure, or death.
 
By taking part in our research study, you can help us make better dengue vaccines that may be used to prevent the virus. Join our compensated study today!

Additional Information

We want to see if the study vaccine is safe and can make an immune response. We also want to see if side effects and immune responses are different depending on a person’s previous dengue infections.

You may qualify for this study if you meet the following criteria.

Eligibility Criteria:

  • 18 – 59 years old
  • Have lived in or traveled to regions where dengue is common (i.e. South Asia, Southeast Asia, Caribbean, Central/South America) or have experienced a prior dengue infection
  • In general good health
  • History of dengue infection, which we will measure by antibody levels
  • A smaller number of people who have never had dengue will also be enrolled
Once enrolled, this study involves:
  • 11-13 in-person study visits
  • Physical exam
  • Blood draws
  • Questionnaires
  • You will receive one dengue vaccine
  • Safety monitoring
  • Optional lymph node aspiration
There is no cost for you to participate in our research study.