Join our EAT2
Research Study!
Researchers at LSU's Pennington Biomedical Research Center are observing the changes that occur in fat tissue as a result of weight gain and loss and its effects on one's health.
Fast Facts
BMI of 23-35 kg/m2
18 - 42 Years Old
Compensation Provided
Conducted On-Site in Baton Rouge, LA
Study Background
It is common for people to undergo periods of weight cycling (gain and loss); however, the effects of gaining a few pounds, even if the weight is shed thereafter, on the body and health are not known. The ability to expand and change the fat tissue during weight cycling is important for health.
This study will look at the changes that occur in the fat tissue as a result of short-term weight gain and weight loss and the effects on health outcomes.
Once enrolled, participants will be randomly assigned to either a control (weight stable) or overfeeding group. Those in the overfeeding group will partake in an 8-week overfeeding (weight gain) intervention, followed by a weight loss component. Individuals in the control group will remain weight stable during the study (This study requires 2 overnight stays in the Pennington Biomedical Inpatient Unit).
Your participation in this study may help improve researchers’ understanding of how weight cycling can impact your fat tissue and health. You can be compensated up to $1255. Contribute to research, and join our EAT2 study today!
Study Background
It is common for people to undergo periods of weight cycling (gain and loss); however, the effects of gaining a few pounds, even if the weight is shed thereafter, on the body and health are not known. The ability to expand and change the fat tissue during weight cycling is important for health.
This study will look at the changes that occur in the fat tissue as a result of short-term weight gain and weight loss and the effects on health outcomes.
Once enrolled, participants will be randomly assigned to either a control (weight stable) or overfeeding group. Those in the overfeeding group will partake in an 8-week overfeeding (weight gain) intervention, followed by a weight loss component. Individuals in the control group will remain weight stable during the study (This study requires 2 overnight stays in the Pennington Biomedical Inpatient Unit).
Your participation in this study may help improve researchers’ understanding of how weight cycling can impact your fat tissue and health. You can be compensated up to $1255. Contribute to research, and join our EAT2 study today!
Additional Information
You may be able to participate if you meet the following criteria:
- Ages 18-42
- Willing to go through short term changes in body weight
- No history of type 1 or 2 diabetes, PCOS, HIV, hepatitis B or C
- No recent history of cancer
- BMI between 22.5-35.5
- Willing to abstain from the use of any nicotine/tobacco products during the inpatient visits
- Willing to stay overnight at Pennington Biomedical on 2 occasions
Total participation lasts about 9 months. Once enrolled, participants will be randomly assigned to either a control (weight stable) or overfeeding group. Those in the overfeeding group will partake in an 8-week overfeeding (weight gain) intervention, followed by a weight loss component. Individuals in the control group will remain weight stable during the study.
Study procedures include:
- 1 screening visit and 11 study visits
- Blood draws
- Drinking doubly labeled water to measure the number of calories burned
- Drinking heavy water to study the fat cells
- Dietary intervention
- Fat biopsies
- DXA scans (to measure the amount of fat, muscle, and bone in the body)
- MRI and MRS scans (to measure the amount of fat in the abdomen and in the liver)
- Insulin Sensitivity Test
- Overnight stays at PBRC on 2 occasions
BuildClinical recruiting for PenningtonBiomedical