Meth Use Treatment
Research Study

The Center on Substance Use and Health is conducting a study for men who like other men investigating if a medication taken on an as-needed basis may help to reduce meth use. Join today!

Fast Facts

men who like other men

using meth

18-70 years old

Compensation Provided

san francisco bay area

Study Background

HiNT is exploring the potential of the medication oral naltrexone, also known as Revia®, to reduce meth use in men who have sex with men. We want to determine this medication’s effect on meth use and associated HIV risk behaviors. 

In this study you will either get oral naltrexone or placebo (an inactive substance that looks identical to the study drug); you will not get both. You will also receive daily text messages asking if you have used substances, taken your study medication and how you are feeling.

Our work honors San Francisco values and is founded on the core elements of harm reduction.

Additional Information

The purpose of this study is to find out what effects intermittent oral naltrexone (ION), taken on an as-needed basis, has on your meth use and associated HIV risk behaviors.

You may qualify for this study if you meet the following criteria.

Key Criteria:

  • Cisgender male
  • Men who like other men
  • 18-70 years old
  • Using meth

Medication: While in this study, you will be asked to take the study drug or a placebo pill on an as-needed basis for 3 months.

In-person visits: You will visit the study site a total of eight times, where you will wear a sweat patch during the screening visits, answer questions on a computer, and provide urine and other biospecimen samples (blood sample).

Remote visits: You will participate in remote visits a total of nine times, where you will receive computer-based counseling around your substance use and behaviors associated with increased risk of STIs, answer questions on a computer, and provide a urine sample to self-test your urine for meth.

Daily surveys: Outside of these visits, you will receive daily EMA surveys, which will prompt you on your phone. If you have not yet taken your study medication, but have reported high levels of craving, stress, or bad mood, then an additional message, called ecological momentary intervention (EMI), will be sent to your phone.

In return for your time, effort, and travel expenses, you will be paid $80 for the screening visits, $15 for each run-in visit, and $55 for completing the enrollment visit. You will receive $20 for the completion of weekly visits. You will receive $55 for the completion of weeks 4 and 8 visits, and $65 for the completion of week 12 visit. In addition, you will also receive $0.40 for each day that you complete the daily ecological momentary assessments (EMA) series, up to $36 for the duration of the study, to offset the cost of receiving and sending surveys.
In total, you earn up to $556 by completing all study visits and all daily EMA-messaging series.

There is no cost for you to participate in the study.