TIRED-Brain
Sleep Research Study

Researchers at Stanford University are studying whether a first-line behavioral intervention for insomnia can help reduce symptoms of depression. Help advance clinical research and join our study today!

Fast Facts

25-60 Years Old

Having trouble with sleep & mood

Compensation Provided

Conducted in Stanford, CA

Study Background

Sleep is essential for physical and emotional well-being, yet millions of Americans don’t get enough sleep. 

Evidence shows that poor sleep can contribute to negative mental health symptoms by disrupting brain connections that regulate mood and emotions. However, more research is needed to understand how improving sleep may also improve emotional regulation. 

The goal of this study is to test whether a science-backed therapy for sleep disturbance can also help reduce depressive symptoms in people with insomnia. 

Your participation in this study may help investigators develop better treatments for insomnia and mental health symptoms in the future. Further research today and join our compensated study!

Additional Information

The purpose of this research study is to determine whether a first-line behavioral intervention for insomnia can help reduce negative mental health symptoms in individuals with insomnia. 


For more information about this study, please contact 650-721-6089. 

For complaints, concerns, or participant’s rights, contact 1-866-680-2906.

You may qualify for this study if you meet the following criteria.

Key Criteria:

  • Age 25-60
  • Experiencing insomnia for at least 3 months
  • Experiencing depressive symptoms
  • Living within 60 miles of Stanford University

This study consists of 9 study visits in total (2 online assessments, 3 in-person visits, and 6 online treatment sessions). During each of the 3 in-person visits, you will be asked to come to Stanford University during the evening to be set up with a sleep monitoring device for you to sleep in at your own home. You will be asked to return the following morning for an MRI scan after the first and third in-person visits. All online sessions will be conducted over Zoom. 

You will be compensated for your time. Please contact study staff for more information.

There is no cost to participate in this research study.