Smoking Cessation Research Study

Yale University researchers are partnering with regular smokers who are motivated to quit to evaluate potential treatments. Join our compensated study today!

Fast Facts

18 years and older

Smoked daily in the past year and motivated to quit

Compensation Provided

Conducted in new haven, CT

Study Background

The purpose of this research study is to evaluate how the medications Varenicline in combination with Guanfacine, or Varenicline alone, influences smoking behavior and can be use for smoking cessation. Guanfacine is a medication used to treat blood pressure, and Varenicline is a medication used to help people quit smoking.

If you decide to participate in the study, you will receive the study medication plus brief smoking session coaching sessions over a 12-week period. You can receive up to $1,020 for completing the entire study. 

Help advance research and join our compensated study today!

HIC# 2000026630

Additional Information

The purpose of this study is to examine the efficacy and mechanisms of combining varenicline and guanfacine for smoking cessation.

You may qualify for this study if you meet the following criteria.

Key Criteria:

  • 18+ years old
  • Able to read and write English
  • Smoked daily in the past year
  • Able to take oral medications and willing to adhere to medication regimen 
  • Motivated to quit smoking 
  • Able to take oral medications and willing to adhere to medication regimen 
  • Can make reasonable transportation arrangements to the study site

If you are interested in participating, you will be asked to complete a screening interview to determine your eligibility. During this time, you will be asked questions about your smoking, and health history and you will fill out some paperwork. 

If you are eligible, you’ll be randomly assigned to take either Varenicline and Guanfacine or Varenicline alone. You will be asked to take the study medication for 12 weeks and attend brief, weekly counseling sessions that will go over different topics to help you with quitting smoking. 

Once you have finished the 12 weeks of treatment, you will be given a 5-day supply of medication to taper you off the study medication. You will attend follow-up appointments, scheduled 1 month and 3 months after you have finished the 12 weeks of treatment.

You can earn up to $1,020 for completing the entire study.

There is no cost for you to participate in this study.