Bipolar Disorder
Research Study
Researchers at the University of Pittsburgh are conducting a research study to learn more about bipolar disorder and to predict who is at high risk of having a mood recurrence in the next 1-3 months. Participants ages 14-25 with diagnosed bipolar disorder are encouraged to apply.
Fast Facts
diagnosed with Bipolar Disorder-I or Bipolar Disorder-II
Currently in remission (no mood symptoms for 8 weeks prior to study entry)
14-25 years old
Compensation Provided
Conducted in continental uS
Study Background
Investigators at the University of Pittsburgh have developed a “risk calculator” to determine the likelihood of whether an adolescent or young adult with bipolar disorder will have a mood (mania, hypomania, or depression) recurrence within 1 to 5 years.
The risk calculator is a mathematical tool that uses several clinical factors (such as the age of the first episode, family history of bipolar disorder, etc.) to determine the likelihood that a specific individual will have a mood recurrence within a specified period of time.
The purposes of the PROMPT-BD research study are 1) to test whether this “risk calculator” accurately predicts mood recurrences that occur within 2 years in adolescents and young adults with Bipolar Disorder, 2) to learn how well passive sensing through a smartphone app measures sleep in adolescents and young adults with Bipolar Disorder, and 3) to learn if the sleep and activity information obtained through actigraphy and the smartphone passive sensing application allow prediction of an immediate (1-4 weeks) mood recurrence.
Ultimately, we hope to better understand how patterns of sleep and activity in adolescents and young adults with Bipolar Disorder can predict the risk of an immediate recurrence and help clinicians use this information proactively to prevent a new mood episode.
Study Background
Investigators at the University of Pittsburgh have developed a “risk calculator” to determine the likelihood of whether an adolescent or young adult with bipolar disorder will have a mood (mania, hypomania, or depression) recurrence within 1 to 5 years.
The risk calculator is a mathematical tool that uses several clinical factors (such as the age of the first episode, family history of bipolar disorder, etc.) to determine the likelihood that a specific individual will have a mood recurrence within a specified period of time.
The purposes of the PROMPT-BD research study are 1) to test whether this “risk calculator” accurately predicts mood recurrences that occur within 2 years in adolescents and young adults with Bipolar Disorder, 2) to learn how well passive sensing through a smartphone app measures sleep in adolescents and young adults with Bipolar Disorder, and 3) to learn if the sleep and activity information obtained through actigraphy and the smartphone passive sensing application allow prediction of an immediate (1-4 weeks) mood recurrence.
Ultimately, we hope to better understand how patterns of sleep and activity in adolescents and young adults with Bipolar Disorder can predict the risk of an immediate recurrence and help clinicians use this information proactively to prevent a new mood episode.
Additional Information
You may qualify for this research study if you meet the following criteria.
Key Criteria:
14-25 years old (Participants younger than 18 years old must have a parent that is also willing to participate.)
Diagnosed with Bipolar Disorder-I or Bipolar Disorder-II and currently in remission (no mood symptoms for 8 weeks prior to study entry)
- No diagnosis of Autism Spectrum Disorder, Intellectual Disability, Schizophrenia, or serious medical conditions that could impact ability to participate
If eligible, participation involves:
- PROMPT-BD involves completing 6 virtual interviews- two at the beginning of the study to determine eligibility and then once every 6 months for 2 years.
- Participation also involves completing online questionnaires and wearing an activity monitor for 2 weeks at each of 5 study time points.
- Installing an app on your smartphone for the duration of the study.
