Rheumatoid Arthritis
Research Study

Researchers at Northwestern Medicine are evaluating a possible cell therapy for people with rheumatoid arthritis who do not benefit from the standard therapies. Join our compensated study today!

Fast Facts

moderate to severe rheumatoid arthritis

unsuccessful prior treatments

Ages 18-70

compensation provided

conducted in Chicago, IL

Study Background

Researchers at Northwestern Medicine are investigating a possible new option for people with rheumatoid arthritis (RA). 

The trial cell therapy is made from a participant’s own cells. By adding new DNA (instructions that tell cells how to do their job) to certain immune cells, cell therapy may help reduce inflammation, joint damage, and other symptoms in people with RA.

Findings from this clinical research study will determine if your own cells can be directed to manage RA and improve your condition.

The trial lasts about 11 months. Participants will attend approximately 5-6 screening visits, 16 treatment study visits, and follow-up visits.

Further research today and join our compensated study!

Additional Information

The purpose of this research study is to investigate whether a trial cell therapy made from a participant’s own cells can be directed to improve RA symptoms and manage the disease.

You may qualify for this study if you meet the following criteria.

Key Criteria:

  • Ages 18-70
  • Moderate to severe rheumatoid arthritis
  • Unsuccessful prior treatments
  • Diagnosed in adulthood

Once enrolled, this study involves the following periods:

  • Screening (about 4 weeks)
    • Complete screening assessment for about 4 weeks to find out if you qualify for the trial
    • Includes a joint biopsy (a needle is used to collect a sample of synovial fluid and tissue)
  • Cell Therapy Preparation (about 6 weeks, but up to 6 months is allowed)
      • Apheresis (blood is drawn into an approved apheresis machine to separate the cells used for the cell therapy)
      • Pre-trial health assessment to confirm that it is safe to receive the cell therapy
  • Cell Therapy and Trial Health Assessments (about 11 months)
    • If you qualify, you will receive the cell therapy as a one-time IV infusion on Day 1 of the trial
    • You will be asked to stay overnight at the trial clinic, so
      the trial doctor and staff can monitor your health closely
    • Receive trial health assessments for 48 weeks (about
      11 months) that include, but are not limited to,
      the following:
      • Joint biopsy (a needle is used to collect a sample of
        synovial fluid and tissue)
      • Vital signs, blood tests, questionnaires, urine tests,
        heart tests, and physical exams
  • Long-term Follow-up (up to 15 years)
    • Continue to the long-term follow-up period for up to
      15 years (you will receive more information from the trial staff)
  •  

Compensation is provided up to $2900 for your participation.

There is no cost for you to participate in this study.