Peripheral Artery Disease (PAD)
Research Study
Researchers at the University of Virginia are investigating the effects of beetroot juice on walking ability in people with blockages in their leg arteries. Join our compensated study today!
Fast Facts
Symptoms or discomfort in your legs when walking that resolves when resting OR diagnosis of peripheral artery disease (pAD)
no use of wheelchair or walker
ages 50+
compensation provided
conducted in charlottesville and culpeper, VA
Study Background
Researchers at the University of Virginia are evaluating whether beetroot juice can reverse functional impairment in adults with peripheral artery disease (PAD).
Beetroot juice is made from beets and early evidence suggests drinking beetroot juice may improve blood flow to the legs and leg muscle function.
Participants will complete baseline evaluations consisting of testing for blockages in the leg arteries, questionnaires, walking and balance tests, MRI, blood draw, and a tongue swab. Additionally, you will be asked to drink the study beverage twice daily for 4.5 months and return for follow-up testing.
Further research today and join our compensated study!
Study Background
Researchers at the University of Virginia are evaluating whether beetroot juice can reverse functional impairment in adults with peripheral artery disease (PAD).
Beetroot juice is made from beets and early evidence suggests drinking beetroot juice may improve blood flow to the legs and leg muscle function.
Participants will complete baseline evaluations consisting of testing for blockages in the leg arteries, questionnaires, walking and balance tests, MRI, blood draw, and a tongue swab. Additionally, you will be asked to drink the study beverage twice daily for 4.5 months and return for follow-up testing.
Further research today and join our compensated study!
Additional Information
The purpose of this research study is to investigate the effects of beetroot juice on walking ability in people with blockages in their leg arteries.
You may qualify for this study if you meet the following criteria.
Key Criteria:
- Ages 50+
- Symptoms in your legs when walking that resolves when resting OR diagnosis of peripheral artery disease (PAD)
- No use of wheelchair or walker
- No above or below knee amputation
- Walking is not limited by symptoms other than PAD
- No foot ulcer on bottom of foot
- No planned major surgery, coronary or leg revascularization in the next 5 months
- No major medical illnesses
- No allergy to beetroot
- English speaking
- No participation in or completion of a clinical trial in the last three months
- No visual impairment that limits walking ability.
- No participation in a supervised treadmill exercise program in previous three months
- Not using an antibacterial mouthwash (such as Cepacol)
- Moderate to severe rheumatoid arthritis
- Unsuccessful prior treatments
- Diagnosed in adulthoo
Once enrolled, this study involves:
- Completing baseline testing
- Testing for blockages in the leg arteries
- Questionnaires
- Walking and balance tests
- Height and weight
- MRI
- Blood draw
- Microbiome sample (tongue swab)
- Drinking the study beverage twice daily for 4.5 months
- Returning for follow-up testing
Compensation of $50 for study completion. Transportation costs may be provided or reimbursed.
There is no cost for you to participate in this study.