Healthy Volunteer Research Study
Researchers at The Fenway Institute are conducting a healthy volunteer research study to better understand how the immune system responds to study antibodies against HIV.
Fast Facts
Healthy adults assigned female at birth
HIV negative
Compensation
Provided
Conducted in
Boston, MA
Study Background
Researchers at The Fenway Institute are conducting a healthy volunteer research study.
This research study is designed to better understand how the immune system responds to combinations of study antibodies against HIV. The antibodies used in this study are not made from HIV and cannot cause HIV infection.
Researchers are examining the safety, tolerability, and immune responses associated with these antibodies when they are given together at different doses. The study will also look at how long the antibodies remain in the body over time.
Information gained from this research may help guide future HIV prevention and treatment efforts and contribute to the development of new strategies to improve long-term health outcomes.
Study Background
Researchers at The Fenway Institute are conducting a healthy volunteer research study.
This research study is designed to better understand how the immune system responds to combinations of study antibodies against HIV. The antibodies used in this study are not made from HIV and cannot cause HIV infection.
Researchers are examining the safety, tolerability, and immune responses associated with these antibodies when they are given together at different doses. The study will also look at how long the antibodies remain in the body over time.
Information gained from this research may help guide future HIV prevention and treatment efforts and contribute to the development of new strategies to improve long-term health outcomes.
Additional Information
In this research study, researchers at The Fenway Institute are examining how the body’s immune system responds to study antibodies against HIV when given in different combinations and doses. The study focuses on evaluating the safety, tolerability, and immune response to these antibodies, as well as how long they remain in the body. Findings from this research may help inform future HIV prevention and treatment efforts.
You may be eligible for this study if you meet the following criteria:
Inclusion Criteria:
- Ages 18–65
- HIV negative
- Healthy adults assigned female at birth
- Not currently pregnant or breastfeeding
- Willing to use a medically accepted birth control method for the study’s duration, if applicable
Exclusion Criteria:
- Prior HIV infection
- Receipt of immunoglobins within the past 60 days
- Receipt of blood products within the past 120 days
- Injection drug use without a prescription in the past 12 months
The entire study lasts about 12 months. Once enrolled, the study involves:
In the clinic: About 9 visits at the Fenway Institute in Greater Boston. Two of these visits will include receiving the study antibodies through an IV infusion (also called a drip). At each visit, blood samples will be collected to measure how your body responds to the antibodies and how much remains in your system over time. Participants will also complete physical exams, questionnaires, and testing for HIV, other STIs, and pregnancy (if applicable). Some visits may be completed over the phone.
At home: Participants may be asked to complete brief diary entries on their phone to track responses throughout the study.
As a participant, you may receive up to $950 for completing all study visits. Travel costs to and from the Fenway Institute, including ridesharing within 15 miles, parking, and public transportation with a receipt, will also be reimbursed.
There is no cost for you to participate in our research study.