In this research study, we are trying to understand how stress and anxiety affect memory and daily functioning in older adults and their care partners. We aim to better understand the interactions between stress, anxiety, and cognitive function, including how these factors affect both the individual and their care partner. Stress and anxiety are linked to changes in memory, emotional health, and everyday experiences, and we will measure all of these. We also want to see whether a computerized anxiety-reduction program can improve stress, anxiety, and memory outcomes. To do this, we are using evidence-based interventions and guided activities designed to reduce anxiety and support memory in both participants and their care partners.

You may be eligible for this study if you meet the following criteria:

Inclusion Criteria:

• Adults age 60 or older
• Experience stress, anxiety, or memory concerns
• Have a care partner age 18 or older who is willing to participate (spouse, child, or friend)
• Able to read and speak English at a 6th grade level
• Able to use a computer and smartphone

Exclusion Criteria:

• Blindness or deafness that prevents participation in phone screening or computerized tasks
• Terminal illness or severe medical/motor conditions that prevent participation
• Severe or unstable psychological conditions (e.g., untreated schizophrenia or bipolar disorder, recent changes in therapy or medication)
• Cognitive impairment beyond mild levels (screened via MoCA and QDRS scores)
• Significant disinhibition, delusions, or hallucinations above threshold levels

The entire study lasts approximately 6–7 months. Once enrolled, the study involves:

In-person visits: 6 visits including a baseline assessment, two intervention sessions, and three follow-up assessments at 1, 3, and 6 months post-treatment. During these visits, you and your care partner will complete questionnaires, memory and cognitive tasks, and guided intervention activities. Intervention sessions involve either the computerized anxiety-reduction program (CAST) or a health education program (HEC), with support from a trained interventionist.

From home: Between intervention sessions and after the program, you and your care partner will complete brief daily surveys using a phone or tablet app. These surveys ask about stress, mood, and memory and take only a few minutes to complete each day.

As participants, you may receive up to $320.

There is no cost for you to participate in our research study.