Post-Bariatric Surgery Paid Research Study
The WISE Brain Study investigates how weight loss and changes in diabetes status following bariatric surgery affect brain function and cognition over time.
Fast Facts

Individuals who have had weight loss surgery between 3-10 years ago

25-75
Years Old

Compensation
Provided

Conducted in
UF Health Gainesville or Jacksonville, FL
Study Background
The WISE Brain Study investigates how weight loss and changes in diabetes status following bariatric surgery affect brain function and cognition over time.
Adults who have undergone bariatric surgery are invited to participate. The study involves two in-person visits over two days, totaling approximately six hours. During these visits, participants will complete health questionnaires, provide a small blood sample, participate in thinking and memory tasks, and receive an MRI brain scan. Researchers will also review participants’ medical records related to their surgery. The study is funded by the National Institute of Diabetes and Digestive and Kidney Diseases and does not involve any clinical treatment. Participation is voluntary, and compensation is provided for time and travel.
Additional Information
This study aims to better understand the long-term effects of weight loss and improved diabetes status after bariatric surgery on brain structure and cognitive function. The findings may contribute to future research on the prevention and treatment of degenerative brain disorders such as dementia and Alzheimer’s disease.
You may be eligible for this study if you meet the following criteria.
Inclusion Criteria:
Adults who have undergone weight loss surgery between 3-10 years ago
Able to travel to Gainesville or Jacksonville, FL for two in-person assessments
Ages 25-75
Speak English
Participants will attend two in-person visits at the University of Florida.
Visit 1 (3–4 hours): Includes informed consent review, blood draw, detailed health and medical history questionnaires, and cognitive testing.
Visit 2 (1.5–2 hours): Includes MRI safety screening and a one-hour brain scan. Women of childbearing potential will receive a pregnancy test prior to the optional MRI. Participants may also be asked to provide medical records related to their bariatric surgery.
As a participant, you may receive up to $195.
There is no cost for you to participate in our research study. Compensation is provided for travel.