Chronic Pain Research Study

Researchers at Massachusetts General Hospital are conducting a remote study with adults currently using opioid medication daily for chronic pain to learn how medical marijuana may affect opioid use for pain management.

Fast Facts

Chronic pain for 6+ months

Use opioid pain medication daily

Not a regular user of cannabis

Remote

Study Background

Researchers at Massachusetts General Hospital are conducting a study with adults currently using opioid medication daily for chronic pain to learn how medical marijuana may affect opioid use for pain management.

This six month study aims to to see whether medical marijuana might help adults ages 18-75 with chronic pain gradually reduce or taper their dose of opioid medications. Participants will take part in a 24-week Prescription Opioid Taper Support program in which they will discuss pain management, opioid use, and other topics with a trained clinician and other participants. Some participants may be able to start using medical marijuana in addition to this program, while others will be asked to wait 6 months before trying medical marijuana products.

If you are an adult aged 18-75 who currently uses opioid medication daily for chronic pain, and are interested in trying cannabis to reduce pain, we invite you to apply. Participants may receive up to $1150.

Study Background

Researchers at Stanford University are conducting a study in adolescents and adults ages 12 and older to evaluate an investigational medication for non-segmented vitiligo.

Vitiligo is a common chronic autoimmune disorder of the skin which presents as patches of pigment loss. Currently, there are no known cures or preventive options for vitiligo, and few treatment options exist. In this research study, we want to test the safety and effectiveness of an investigational drug called upadacitinib. 

If you are 12 years or older and have non-segmental vitiligo, you may be eligible to participate. Eventually, we hope the findings of this study might be useful for treating vitiligo and improving people’s quality of life.

Additional Information

Researchers at Massachusetts General Hospital are conducting a study with adults ages 18-75 who are currently using opioid medication daily for chronic pain to learn how medical marijuana may affect opioid use for pain management.

You may qualify for a study if you meet the following criteria.

Qualified Participants:

  • Ages 18-75
  • Chronic pain for 6+ months
  • Use opioid pain medication daily
  • Not a regular user of cannabis
  • Interested in trying cannabis to reduce pain or opioid dose.
  • No cognitive disorder (such as dementia)

Everyone in this study will participate in a 24-week Prescription Opioid Taper Support (POTS) program. POTS sessions will last approximately 1 hour per week and will include group discussions on pain management and opioid use.

In addition, participants will also have 8 study visits (either in person or via Zoom) over the course of the 24 weeks. Most study visits will last 1-1.5 hours, where participants will complete surveys, fill out questionnaires, and complete cognitive tasks.

There is no cost for you to participate in our research study. Participants will be responsible for the costs of any marijuana they choose to purchase.

Qualified participants will receive up to $1150.

For further information, you can e-mail the study team at potsandmm@mgh.harvard.edu or call (617)-643-5039.