Depression Research Study

Researchers at the University of California San Francisco are conducting a study to learn more about the relationship between the gut microbiome, oral microbiome, and psychiatric symptoms.

Fast Facts

Ages 21-60

Experiencing Symptoms of Depression

Compensation Provided

Conducted in
San Francisco, CA

Study Background

Join the Cellular Aging and Neurobiology of Depression (CAN-D) study!

In this study, we want to learn more about the roles of the oral microbiome and the gut microbiome. Specifically, we will be investigating the different roles they play in individuals with depression compared to individuals without depression.

Through this study, we hope to better understand how changes in the gut microbiome and oral microbiome affect psychiatric symptoms, and how these microbiomes may recover with antidepressant treatment. 

Study Background

Join the Cellular Aging and Neurobiology of Depression (CAN-D) study!

In this study, we want to learn more about the roles of the oral microbiome and gut microbiome. Specifically, we will be investigating the different roles they play in individuals with depression compared to individuals without depression.

Through this study, we hope to better understand how changes in the gut microbiome and oral microbiome affect psychiatric symptoms, and how these microbiomes may recover with antidepressant treatment. 

Additional Information

The purpose of this research study is to better understand how changes in the gut microbiome and oral microbiome affect psychiatric symptoms, and how these microbiomes may recover with antidepressant treatment. 

You may qualify for a study if you meet the following criteria.

Inclusion Criteria:

  • Ages 21-60
  • Experiencing symptoms of depression
  • Willing to provide stool/saliva samples

The entire study will last approximately 10 weeks and will include 4 in-person visits. Some participants may be treated for 8 weeks with an SSRI (selective serotonin reuptake inhibitor; fluoxetine, sertraline, escitalopram, or citalopram).

Study visits may include:

  • Interviews
  • Saliva, stool, and blood samples
  • Mood rating scales
  • Behavioral measures

As a participant, you can receive up to $275 for completing all study tasks.

There is no cost for you to participate in our research study.