Autosomal Dominant Polycystic Kidney Disease (ADPKD) Research Study
Researchers at the University of Colorado Anschutz Medical Campus are conducting a study to learn more about the impact of antibiotic use on kidney stones in people with ADPKD.
Fast Facts
Ages 18-60
Diagnosed with ADPKD
Compensation Provided
Recruiting Across the Entire United States
Study Background
Researchers at the University of Colorado Anschutz Medical Campus are looking for individuals ages 18-60 who are diagnosed with ADPKD and no kidney stones in the past 5 years.
We are conducting a research study in adults with autosomal dominant polycystic kidney disease (ADPKD) to determine if kidney stone disease affects the rate of kidney disease progression.
Our team will determine if kidney stones affect the rate of ADPKD progression and identify the role of the gut microbiome in stone formation in ADPKD. These results will provide key insights for future studies of kidney stone prevention in ADPKD.
Study Background
Researchers at the University of Colorado Anschutz Medical Campus are looking for individuals ages 18-60 who are diagnosed with ADPKD and no kidney stones in the past 5 years.
We are conducting a research study in adults with autosomal dominant polycystic kidney disease (ADPKD) to determine if kidney stone disease affects the rate of kidney disease progression.
Our team will determine if kidney stones affect the rate of ADPKD progression and identify the role of the gut microbiome in stone formation in ADPKD. These results will provide key insights for future studies of kidney stone prevention in ADPKD.
Additional Information
The goal of this study is to learn if kidney stone disease affects the rate of disease progression and to determine whether the frequency of certain antibiotic use increases the risk for stone disease in ADPKD.
You may qualify for a study if you meet the following criteria.
Inclusion Criteria
- A diagnosis of ADPKD
- No kidney stones within the previous 5 years
- GFR >45 mL/min/1.73 m2
- Recent antibiotic use (within the previous 6 months) or no antibiotic use within the previous 3 years
This research study will consist of a one-time visit to the Renal Research Clinic located at the University of Colorado Anschutz Medical Campus consisting of:
- Blood draw, urine samples, stool sample, and assessment of lab values
- Measurement of resting blood pressure and heart rate
- Health and diet questionnaires
Qualified participants are compensated.
Travel to the research clinic will be paid for by the study.