Healthy Volunteer Research Study
Researchers are investigating a vaginal birth control ring that may also help prevent sexually transmitted infection.
Fast Facts
Women ages 21+
Using birth control (hormonal or non-hormonal)
Generally healthy
Compensation Provided
Conducted in New York City
Study Background
Researchers are investigating a vaginal birth control ring that may also help prevent sexually transmitted infection. This study is not testing if the study ring works to prevent pregnancy or sexually transmitted infection. We are looking at whether the ring is safe and well tolerated; in addition, we will gather information about how the medications are circulated through the body when the ring is used for 1 month.
The study medications are released via a self-administered vaginal ring. The ring contains levonorgestrel (a type of progestin used in many currently approved birth control methods) and dapivirine (an investigational medication being developed to prevent HIV). The study is looking at two different doses of the study drug by randomly assigning participants to one combination or the other.
Additional Information
In this research study, we want to look at how the study drugs are circulated through the body, to find out if the ring is safe and well-tolerated, and to look at the effects of the ring on vaginal bleeding.
You may qualify for a study if you meet the following criteria.
Inclusion Criteria:
- Are ages 21+
- Were assigned female sex at birth and are not currently on female-to-male transition therapy
- Are protected from pregnancy by either hormonal or non-hormonal contraception, or not at risk for pregnancy (e.g copper IUD, condoms, abstinence, sterilization, same-sex partner)
- Are generally healthy
- Have a regular menstrual cycle (21-35 days)
Participation in the study will last approximately 3 months. This includes three months of active ring use, screening procedures, and up to four phone contacts in the three months following ring removal. There will be 5 in-person clinic visits. Participants may have a virtual visit prior to the first clinic visit to review the informed consent form. The most frequent study procedures include blood draws and pelvic exams.
Yes, participants will be compensated up to $750 for completing all parts of the study.
There is no cost for you to participate in our research study.