Rosacea Research Study

Researchers at Icahn School of Medicine at Mount Sinai are conducting a study to evaluate possible treatments for individuals living with rosacea.

Fast Facts

Individuals ages 18 and older

Have a history of rosacea with inflamed bumps

Compensation Provided

Conducted in New York, NY

Study Background

Researchers at Icahn School of Medicine at Mount Sinai are conducting a study to evaluate possible treatments for individuals living with rosacea.

Rosacea causes swelling and redness by inflaming blood vessels, nerves, and the immune system. Triggers like germs, heat, stress, spicy food, alcohol, and sunlight can make these symptoms worse.

PF-07038124 is a medicine that treats rosacea by reducing inflammation. It blocks PDE4, a substance linked to inflammation, which helps ease skin problems caused by rosacea. Researchers believe that using PF-07038124 as a cream could improve immune-related issues in different types of rosacea and make the skin healthier.

In short, rosacea inflames the skin, affecting blood vessels, nerves, and the immune system. PF-07038124 targets these problems by blocking PDE4 and might be a good treatment for rosacea.

Study Background

Researchers at Icahn School of Medicine at Mount Sinai are conducting a study to evaluate possible treatments for individuals living with rosacea.

Rosacea causes swelling and redness by inflaming blood vessels, nerves, and the immune system. Triggers like germs, heat, stress, spicy food, alcohol, and sunlight can make these symptoms worse.

PF-07038124 is a medicine that treats rosacea by reducing inflammation. It blocks PDE4, a substance linked to inflammation, which helps ease skin problems caused by rosacea. Researchers believe that using PF-07038124 as a cream could improve immune-related issues in different types of rosacea and make the skin healthier.

In short, rosacea inflames the skin, affecting blood vessels, nerves, and the immune system. PF-07038124 targets these problems by blocking PDE4 and might be a good treatment for rosacea.

Additional Information

Researchers at the Icahn School of Medicine at Mount Sinai are studying potential treatments for people suffering from rosacea. The study aims to assess effective therapies for individuals affected by this condition.

You may qualify for this study if you meet the following criteria.

Inclusion Criteria:

  • Ages 18+
  • Have a history of rosacea with inflamed bumps (papulopustular rosacea)
  • No history of HIV, hepatitis, or tuberculosis
  • Not pregnant, nursing or planning a pregnancy, and willing to use birth control during the entire study
  • Not currently receiving another investigational product
  • Able to attend clinic visits every 4 weeks at the site location in New York City for a total of 5 visits

This study will include 5 visits over the course of 12 weeks, as outlined below:

Baseline/Week 0 Visit:

  • Clinical assessments
  • Review of concomitant medications
  • Standardized clinical photography
  • Questionnaires
  • Collection of skin tape-strip samples (lesional and nonlesional facial skin)
  • Collection of baseline blood samples

Week 4 Visit:

  • Clinical assessments (including photography and questionnaires)
  • Collection of skin tape-strip samples (lesional facial skin)

Week 8 Visit:

  • Clinical assessments (including photography and questionnaires)
  • Collection of skin tape-strip samples (lesional facial skin)
  • Collection of blood samples for storage (or early termination if applicable)

Week 12 Visit:

  • Clinical assessments (including photography and questionnaires)
  • Collection of skin tape-strip samples (lesional facial skin)

If you agree to take part in this study, you will be paid $280 for your time and effort. If you do not complete all visits, then you will be paid $70 for each visit you complete (Baseline, Week 4, Week 8, and Week 12). Payment will be given to you in the form of a check at the end of the study.

There is no cost for you to participate in our research study.