Psychosis Research Study
Johns Hopkins University is conducting a study on how nasal function might impact the brain in early stage psychosis.
Fast Facts
Ages 16-35
Diagnosed with a Psychotic Disorder
Compensation Provided
Conducted in Baltimore, MD
Study Background
Researchers at Johns Hopkins University are seeking to understand the disease mechanism and to improve the treatment of psychotic disorders.
This study involves examining nasal pathology and brain structure/function in patients with early-stage psychosis.
Participants will undergo clinical and cognitive assessments, a smell test, blood draw, tissue biopsy, and a brain scan with MRI technology.
Join our compensated study!
Study Background
Researchers at Johns Hopkins University are seeking to understand the disease mechanism and to improve the treatment of psychotic disorders.
This study involves examining nasal pathology and brain structure/function in patients with early-stage psychosis.
Participants will undergo clinical and cognitive assessments, a smell test, blood draw, tissue biopsy, and a brain scan with MRI technology.
Join our compensated study!
We are conducting two investigations. The first study examines the relation between stress and well-being in teens. This study involves completing a brief online survey that takes about 10 minutes. Participants receive a $10.00 gift card for completing the survey.
The second study compares the efficacy of different online programs that aim to help teens cope with stress and build resilience. The purpose of these programs is to reduce or prevent feelings of depression and anxiety in teens who may be at risk for such mood problems.
Teens can participate in the short survey study. They also may be offered the opportunity to participate in a no-cost program for managing stress.
Findings from this study will help us learn ways to prevent anxiety and depression in youth.
Additional Information
The purpose of this study is to understand the disease mechanism and to improve the treatment of psychotic disorders.
You or your child may qualify for this study if you/they meet the following criteria.
Inclusion Criteria:
- Ages 16-35
- Diagnosed with a psychotic disorder (e.g., schizophrenia, schizoaffective, bipolar disorder/depression with psychotic features)
- Have experienced first psychotic episode (e.g., hallucinations, hearing voices, talking incoherently) in the last 2 years
- No dependence on substances other than cannabis (e.g, alcohol, opioids, stimulants)
- Able to undergo MRI scan (no claustrophobia, no metal in the body)
- No history of head trauma, neurological disorder, or mental retardation
- No medical diagnosis of HIV, hepatitis, or related infectious disease
- Live within 150 miles of Baltimore, MD (Including MD, DE, PA, VA, DC, and WV)
The study participant will undergo comprehensive clinical (symptomatic and cognitive) assessments, blood draw, olfactory neuron biopsy, and brain scan. All will be done in the Johns Hopkins Hospital, although clinical assessments may be done remotely (via Zoom). We also expect the study participants to be back in two years for clinical and brain imaging assessments (no need of olfactory neuron biopsy in the second time).
Compensation is provided up to $400 for your participation. The transportation will also be provided.
There is no cost for you to participate in this study.
