Smoking Research Study
Researchers at Baylor College of Medicine are testing a treatment to help individuals both quit smoking and prevent post-quit weight gain.
Fast Facts
18-75 Years Old and Have Been Smoking Cigarettes for over 1 Year
Desire to Quit Smoking
Have Higher than Normal Blood Sugar And/or Are Overweight/Obese
Compensation Provided
Conducted in Houston, TX
Study Background
Researchers at Baylor College of Medicine are testing exenatide as a supplementary treatment to help individuals quit smoking while reducing post-quit weight gain.
Many smokers experience weight gain after quitting cigarettes, which can discourage them from making the decision to stop smoking altogether. Identifying a treatment that can both help smokers quit cigarettes and mitigate post-quit weight gain could help address a major obstacle to quitting smoking.
This study aims to test exenatide, an injectable medication used to control blood sugar in people with type 2 diabetes, as a treatment for smoking cessation and prevention of post-quit weight gain. We will compare quit rates and post-quit weight gain between participants using only nicotine patches and those using exenatide as a supplementary treatment alongside nicotine patches to determine exenatide’s effectiveness.
Study Background
Researchers at Baylor College of Medicine are testing exenatide as a supplementary treatment to help individuals quit smoking while reducing post-quit weight gain.
Many smokers experience weight gain after quitting cigarettes, which can discourage them from making the decision to stop smoking altogether. Identifying a treatment that can both help smokers quit cigarettes and mitigate post-quit weight gain could help address a major obstacle to quitting smoking.
This study aims to test exenatide, an injectable medication used to control blood sugar in people with type 2 diabetes, as a treatment for smoking cessation and prevention of post-quit weight gain. We will compare quit rates and post-quit weight gain between participants using only nicotine patches and those using exenatide as a supplementary treatment alongside nicotine patches to determine exenatide’s effectiveness.
Additional Information
Through this study, we aim to determine whether use of exenatide as a supplementary treatment alongside nicotine patches can help individuals quit smoking while reducing post-quit weight gain.
You may qualify for this study if you meet the following criteria.
Inclusion Criteria:
- 18-75 years old
- Have been smoking cigarettes for over 1 year
- Desire to quit smoking
- Have higher than normal blood sugar and/or are overweight/obese
Participants will complete 17 visits over the course of 27 weeks. This will include a screening visit, 14 weekly clinic visits during the treatment portion of the study, and 2 follow-up visits during weeks 15 and 26. Participants will receive treatment – either exenatide or a placebo alongside a nicotine patch – for 2 weeks before the target quit day and 12 weeks afterwards. Throughout the study, we will also collect biological samples including blood, urine, and breath samples.
Participants can receive up to $580 for their time and effort.
There is no cost for you to participate in our research study.