This study is being conducted to evaluate a potential treatment for recurrent herpes labialis, commonly known as cold sores. Researchers want to better understand how the study treatment works when started during the earliest symptoms of an outbreak, such as tingling, itching, or burning.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Get frequent cold sores (3 or more in the past year)
• Usually feel itching, tingling, or burning before a cold sore appears
• Cold sores usually form blisters or sores
• Ages 18+

Participation includes several steps:

1. Screening Visit
   You will meet with the study team, review the study details, provide consent, and complete screening procedures to determine eligibility.
2. Run-in Phase
   After screening, participants wait for the start of a new cold sore episode while tracking symptoms and remaining in contact with the study team.
3. Visit 1 (Treatment Start)
   If symptoms begin, participants must visit the study site within 12 hours of symptom onset. The study team will confirm eligibility, assess the lesion, and begin study treatment.
4. Treatment Period
   Participants will apply the study product 5 times daily for up to 10 days and complete a daily electronic diary about symptoms and healing progress. A follow-up phone call will also occur on Day 2 or 3.
5. Visit 2 (End of Study)
   Participants will return for a final assessment, diary review, and safety evaluation once the lesion has healed or by Day 10.

Study Locations

Wrocław, Poznań, Gdańsk, Gdynia , Częstochowa , Łódź

Study Locations:

Wrocław, Poznań, Częstochowa, Łódź

There is no cost for you to participate in our research study.