Menstrual Health Research Study

Researchers at Oregon Health and Science University are studying the differences in blood clotting proteins found in the menstrual blood of people with heavy periods versus those with normal periods, and how these clotting proteins are managed in the body.

Fast Facts

Menstruating Individuals ages 18+

Have regular periods

Compensation Provided

Conducted in Portland, OR

Study Background

The HEEC: Clotting Factors and Heavy Menstrual Bleeding Study is focused on understanding the role of clotting proteins in menstrual blood, specifically comparing individuals with heavy periods to those with normal periods. Researchers aim to identify differences in the types and amounts of clotting proteins present in the menstrual blood of both groups. By examining these differences, the study seeks to gain a deeper understanding of how clotting factors are controlled within the body and how they might contribute to heavy menstrual bleeding (HMB). This research could offer valuable insights into the causes of HMB and help identify new treatment options for those affected by it.

To achieve these goals, the study will collect menstrual blood samples from participants using a provided menstrual cup, while tracking pad and tampon usage throughout the menstrual cycle. Participants with both heavy and normal menstrual bleeding are needed to compare the two groups effectively. The study will be conducted over the course of one menstrual period, with participants attending multiple in-person visits at Oregon Health and Science University (OHSU). Ultimately, the findings from this study could provide a better understanding of the biological mechanisms behind heavy periods and lead to more effective treatments for those who experience them.

Join our compensated study!

Study Background

The HEEC: Clotting Factors and Heavy Menstrual Bleeding Study is focused on understanding the role of clotting proteins in menstrual blood, specifically comparing individuals with heavy periods to those with normal periods. Researchers aim to identify differences in the types and amounts of clotting proteins present in the menstrual blood of both groups. By examining these differences, the study seeks to gain a deeper understanding of how clotting factors are controlled within the body and how they might contribute to heavy menstrual bleeding (HMB). This research could offer valuable insights into the causes of HMB and help identify new treatment options for those affected by it.

To achieve these goals, the study will collect menstrual blood samples from participants using a provided menstrual cup, while tracking pad and tampon usage throughout the menstrual cycle. Participants with both heavy and normal menstrual bleeding are needed to compare the two groups effectively. The study will be conducted over the course of one menstrual period, with participants attending multiple in-person visits at Oregon Health and Science University (OHSU). Ultimately, the findings from this study could provide a better understanding of the biological mechanisms behind heavy periods and lead to more effective treatments for those who experience them.

Join our compensated study!

Additional Information

This study aims to understand how blood clotting proteins differ between people with heavy periods and those with normal periods, and how these proteins are managed in the body. The goal is to uncover the causes of heavy bleeding and improve treatment options.

You may qualify for this study if you meet the following criteria.

Inclusion Criteria:

  • Menstruating individuals ages 18+
  • Have regular periods (every 21-35 days)
  • Do not use hormonal contraception (e.g., pill, patch, injection, implant, or IUD) or copper IUD
  • Willing to use study-provided disposable pads or tampons along with a menstrual cup for one menstrual cycle
  • Not pregnant or breastfeeding
  • No known bleeding disorder, uterine fibroids, or polyps 
  • Willing to refrain from sexual intercourse with someone who can get you pregnant for two weeks

Once enrolled, this study involves:

    • Screening/Enrollment Visit: You will attend an in-person visit, scheduled at your convenience, where you will review the study requirements with the study staff and receive all necessary materials.

    • Second Visit: Within 24 hours of the start of your first study period, you will return for a second visit. During this visit, you will have a blood draw and provide your first menstrual blood sample.

    • Daily Sample Drop-offs: Throughout your menstrual period, you will drop off a sample of your menstrual blood each day at the study site.

    • Final Visit: About 3 weeks after your first sample drop-off, you will return for a final visit, which will include an endometrial biopsy.

Compensation is provided up to $380 for your participation.

There is no cost for you to participate in our research study.