Menstruation Research Study

Researchers at Washington University School of Medicine are conducting a study to better understand uterine peristalsis and how it may contribute to common side effects associated with Nexplanon contraceptive implants.

Fast Facts

Have a Nexplanon Implant and Are Experiencing No Menstrual Bleeding.

18-37 Years Old

Compensation Provided

Conducted in

St. Louis, MO

Study Background

Researchers at Washington University School of Medicine are conducting a study to better understand uterine peristalsis—mild uterine contractions—and how these patterns may contribute to common side effects experienced with Nexplanon contraceptive implants.

This research focuses on characterizing uterine peristalsis in women with normal cycles as well as those with gynecological conditions such as endometriosis, polycystic ovarian syndrome, or abnormal uterine bleeding associated with Nexplanon. By studying these patterns, researchers hope to uncover insights into the physiological effects of Nexplanon and improve knowledge about its impact on women’s health.

The findings from this study could lead to better management strategies for Nexplanon side effects and contribute to advancements in gynecological care.

Study Background

Researchers at Washington University School of Medicine are conducting a study to better understand uterine peristalsis—mild uterine contractions—and how these patterns may contribute to common side effects experienced with Nexplanon contraceptive implants.

This research focuses on characterizing uterine peristalsis in women with normal cycles as well as those with gynecological conditions such as endometriosis, polycystic ovarian syndrome, or abnormal uterine bleeding associated with Nexplanon. By studying these patterns, researchers hope to uncover insights into the physiological effects of Nexplanon and improve knowledge about its impact on women’s health.

The findings from this study could lead to better management strategies for Nexplanon side effects and contribute to advancements in gynecological care.

Additional Information

This study is being conducted to understand the patterns of uterine peristalsis (mild contractions) in women and how these patterns may contribute to side effects experienced with Nexplanon contraceptive implants. The goal is to improve knowledge about Nexplanon’s impact on uterine function and women’s health.

You may qualify for this study if you meet the following criteria:

Inclusion Criteria:

  • Premenopausal
  • Ages 18-37
  • Have a Nexplanon inserted (no periods)

Exclusion Criteria:

  • Currently pregnant or breastfeeding
  • Have a uterine condition, such as fibroids or abnormal shape
  • Take medications that affect how the uterus moves or contracts (for example, certain birth control or pregnancy-related medications)
  • Feel very anxious in small spaces or can’t have an MRI due to fear or discomfort
  • Have reasons that prevent you from safely having an MRI, like having metal in your body (such as from past surgeries) or weighing over 300 lbs

If you participate in this study, you will attend at least one visit lasting 1-3 hours. During these visits, you may undergo:

  • MRI Scans to observe uterine activity.
  • Blood Draws for hormone or health analysis.
  • Mapping and 3D Scans to gather detailed information about uterine function.
  • Ultrasounds to monitor uterine activity and structure.

As a participant, you can receive up to $275, including $100 per MRI, $100 per mapping, $25 per blood draw, and a $50 completion bonus. Transportation costs (e.g., Uber or taxi) can also be provided if needed.

There is no cost for you to participate in our research study.