Healthy Volunteers Research Study
Researchers at UT Health San Antonio Are Conducting a Study to Better Understand the Progression from Healthy Glucose Levels to Prediabetes and Type 2 Diabetes.
Fast Facts
Generally Healthy With no Chronic Health Conditions
18-55 Years Old
Compensation Provided
Conducted in San Antonio, TX
Study Background
The Researchers at UT Health San Antonio Aim to Uncover Key Factors Driving the Transition from Healthy Glucose Metabolism to Prediabetes.
The researchers at UT Health San Antonio are dedicated to understanding why some individuals progress from healthy glucose metabolism to prediabetes and eventually type 2 diabetes. Through this study, they aim to identify the metabolic, molecular, and genetic differences between individuals with normal glucose tolerance (NGT) and those with prediabetes, specifically those with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). By examining how insulin sensitivity and beta cell function vary across these groups, the researchers hope to pinpoint the underlying mechanisms that cause the decline in beta cell function—a critical factor in the development of type 2 diabetes.
By establishing a control group of healthy individuals with NGT, the researchers will have a baseline for comparison, allowing them to gain insights into the factors that contribute to the progression from normal glucose levels to prediabetes. The findings from this study could help uncover new prevention strategies and potential treatments to slow or halt the decline in beta cell function, offering hope for those at risk of developing diabetes.
Study Background
The Researchers at UT Health San Antonio Aim to Uncover Key Factors Driving the Transition from Healthy Glucose Metabolism to Prediabetes.
The researchers at UT Health San Antonio are dedicated to understanding why some individuals progress from healthy glucose metabolism to prediabetes and eventually type 2 diabetes. Through this study, they aim to identify the metabolic, molecular, and genetic differences between individuals with normal glucose tolerance (NGT) and those with prediabetes, specifically those with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). By examining how insulin sensitivity and beta cell function vary across these groups, the researchers hope to pinpoint the underlying mechanisms that cause the decline in beta cell function—a critical factor in the development of type 2 diabetes.
By establishing a control group of healthy individuals with NGT, the researchers will have a baseline for comparison, allowing them to gain insights into the factors that contribute to the progression from normal glucose levels to prediabetes. The findings from this study could help uncover new prevention strategies and potential treatments to slow or halt the decline in beta cell function, offering hope for those at risk of developing diabetes.
Additional Information
You may qualify for a study if you meet the following criteria.
Inclusion Criteria:
- Age: 18–55
- Generally healthy with no chronic health conditions
- BMI: 21–35
Exclusion Criteria:
- Diagnosis of diabetes or prediabetes
- Uncontrolled chronic medical conditions
- Use of weight loss medications
- Anemia
If you choose to participate in this study, you will complete a total of three visits over the course of approximately one month. Here’s what to expect during each visit:
Screening/Qualification Visit:
During the first visit, which lasts about 3-4 hours, you will undergo a glucose tolerance test and a body fat composition analysis to determine your eligibility for the study.Metabolic Testing Visits:
The following two visits, each lasting about 8 hours, will involve more detailed metabolic studies. These include inserting one or two IV catheters into a vein in your arm to collect blood samples and administer glucose and insulin, which will help test pancreatic function and insulin sensitivity.
All visits are scheduled in the morning and require fasting overnight.
You be compensated for your time and participation—up to $470 in total across all visits.
Additionally, transportation within the San Antonio area will be provided at no cost to you for study visits.
There is no cost for you to participate in our research study.