PTSD Research Study

Researchers at Yale University are conducting a study on PTSD to better understand how traumatic experiences impact the brain.

Fast Facts

Experiencing Symptoms of PTSD

18-40 Years Old

Compensation Provided

Conducted in New Haven, CT

Study Background

This study aims to identify brain activity patterns linked to different PTSD symptom clusters using MRI and MEG scans.

Post-Traumatic Stress Disorder (PTSD) affects millions of people, but not everyone experiences it the same way. Some individuals may struggle with intrusive memories, while others may have emotional numbness or heightened alertness. By studying how the brain responds to different experiences, researchers hope to uncover distinct patterns of brain activity associated with PTSD symptoms.

Participants in this study will complete an interview about their mental health history, followed by two brain scans (MRI and MEG). During these scans, they will talk about past experiences, recognize facial expressions, and listen to recordings of their own memories. The goal is to gain deeper insight into how PTSD affects the brain, ultimately helping to improve diagnosis and treatment options.

Study Background

This study aims to identify brain activity patterns linked to different PTSD symptom clusters using MRI and MEG scans.

Post-Traumatic Stress Disorder (PTSD) affects millions of people, but not everyone experiences it the same way. Some individuals may struggle with intrusive memories, while others may have emotional numbness or heightened alertness. By studying how the brain responds to different experiences, researchers hope to uncover distinct patterns of brain activity associated with PTSD symptoms.

Participants in this study will complete an interview about their mental health history, followed by two brain scans (MRI and MEG). During these scans, they will talk about past experiences, recognize facial expressions, and listen to recordings of their own memories. The goal is to gain deeper insight into how PTSD affects the brain, ultimately helping to improve diagnosis and treatment options.

Additional Information

This study is being done to identify patterns of unique PTSD subtypes.

You may qualify for this study if you meet the following criteria.

Inclusion Criteria:

  • 18-40 years old
  • Experiencing symptoms of PTSD
  • Able to undergo an MRI (no non-removable metal on or in body or severe claustrophobia)
  • College students encouraged to apply

Exclusion Criteria:

  • History of psychosis, schizophrenia, or bipolar disorder
  • Traumatic brain injury
  • Neurological disorders
  • On antipsychotic medication
  • Psychiatry medication changes in past 60 days
Step 1: Clinical Interview (2-4 hours, remote or in-person)
  • Answer questions about your current and past mental health symptoms.
  • This will determine if you meet the study criteria.
Step 2: MRI & MEG Brain Scans (Both on the Same Day)
  • MRI Scan (About 2 hours, 1.5 hours inside the scanner)
    • Tell three personal stories: one traumatic, one happy, and one neutral.
    • View and rate pleasant, neutral, and trauma-related images.
    • Complete a task recognizing facial expressions.
  • MEG Scan (About 2 hours)

    • Listen to audio recordings of the stories you told earlier.
    • Listen to pleasant, neutral, and trauma-related sounds.
    • Repeat the facial expression task.
Location
  • Study takes place in New Haven, CT.
  • Travel within 2 hours of New Haven may be covered.

You will be compensated for your time and participation in the study:

  • $50 for the clinical screening interview
  • $100 for the MRI scan
  • $150 for the MEG scan
  • Total compensation: $300

Additionally, mileage and parking will be reimbursed, and transportation options like Uber or train reimbursement (coach class) are available if needed.

There is no cost for you to participate in our research study.