Apply Now

Meth Use Research Study

Researchers at the Pacific Treatment and Research Center at UC San Diego are trying to evaluate the efficacy of extended-release naltrexone, an injectable medication, plus bupropion (XR-NTX/BUP-XL) pills compared to a placebo, or a sugar pill/inactive medication, to reduce Methamphetamine use in those with moderate to severe Methamphetamine Use Disorder (MUD).

Apply Now

Fast Facts

Ages 18-65

Have a Desire to Quit or Cut Down on Crystal Meth Use

Compensation Provided

Conducted in La Jolla, CA

Study Background

Both of these medications (extended-release naltrexone, an injectable medication, plus bupropion (XR-NTX/BUP-XL) pills) are FDA approved and have been used to treat other health conditions. 

During this time, participants will attend study appointments twice a week at our clinic in La Jolla, which we can offer transportation to if needed. They will also use a smartphone app to record themselves taking the study pills every day. After the 12-week treatment phase, participants complete a taper week to taper off the medication, and two follow up visits, for a total of ~19 weeks of participation including the screening visits.

Study Background

Both of these medications (extended-release naltrexone, an injectable medication, plus bupropion (XR-NTX/BUP-XL) pills) are FDA approved and have been used to treat other health conditions. 

During this time, participants will attend study appointments twice a week at our clinic in La Jolla, which we can offer transportation to if needed. They will also use a smartphone app to record themselves taking the study pills every day. After the 12-week treatment phase, participants complete a taper week to taper off the medication, and two follow up visits, for a total of ~19 weeks of participation including the screening visits.

Apply Now

Additional Information

This study is being conducted to evaluate the efficacy of extended-release naltrexone, an injectable medication, plus bupropion (XR-NTX/BUP-XL) pills compared to a placebo, or a sugar pill/inactive medication, to reduce Methamphetamine use in those with moderate to severe Methamphetamine Use Disorder (MUD).

You may qualify for the study if you meet the following criteria.

Inclusion Criteria:

  • Have a desire to quit or cut down on meth use
  • Willing to attend 2 weekly visits to study center in La Jolla, CA
  • Able to refrain from opioid use for at least 7 days before being given study medication
  • Ages 18-65
  • Speak English (written and verbal)

If you participate in this study, here’s what you can expect:

  • During the screening visits, participants will complete the consent documents allowing us to enroll them in the study, questionnaires, medical history and physical evaluation by a study doctor, blood draw, urine sample collection, and ECG to check heart rhythm.
  • These measures are split across 2-3 visits. During the study visits, participants will also complete questionnaires, a urine sample, and check ins with study clinicians.
  • All visits are done in-person.

Participants can earn up to $1,610 across the course of the study.

There is no cost for you to participate in our research study. Lyft rides are provided.

Terms of Service

Privacy Policy

Terms of Service

Privacy Policy

Tagged