COPD Research Study

Researchers from Johns Hopkins School of Medicine are conducting a study with former cigarette smokers living with COPD to test whether air cleaners can improve indoor air quality and respiratory health.

Fast Facts

Former Smoker Who Has COPD, Chronic Bronchitis, Emphysema, Or Chronic Cough With Symptoms In The Past Year

Aged 40+

Compensation Provided

Conducted in Baltimore, MD

Study Background

This study is testing whether indoor air cleaners can help improve breathing and quality of life in former smokers with COPD.

Researchers at Johns Hopkins School of Medicine are leading a multi-center clinical trial to see if using air cleaners in the home can improve respiratory symptoms, reduce flare-ups, and enhance the quality of life in people living with Chronic Obstructive Pulmonary Disease (COPD). This year-long study is focused on former smokers who have a history of COPD and have experienced at least one moderate or severe flare-up in the past year.

The study is part of a nationwide effort enrolling 770 participants, with about 200 expected at Johns Hopkins. The goal is to find out whether removing pollutants like fine particles (PM) from indoor air can improve health outcomes in people with COPD. Participants will receive air cleaners to install in their homes, and researchers will check in regularly through phone calls and remote environmental monitoring.

Study Background

This study is testing whether indoor air cleaners can help improve breathing and quality of life in former smokers with COPD.

Researchers at Johns Hopkins School of Medicine are leading a multi-center clinical trial to see if using air cleaners in the home can improve respiratory symptoms, reduce flare-ups, and enhance the quality of life in people living with Chronic Obstructive Pulmonary Disease (COPD). This year-long study is focused on former smokers who have a history of COPD and have experienced at least one moderate or severe flare-up in the past year.

The study is part of a nationwide effort enrolling 770 participants, with about 200 expected at Johns Hopkins. The goal is to find out whether removing pollutants like fine particles (PM) from indoor air can improve health outcomes in people with COPD. Participants will receive air cleaners to install in their homes, and researchers will check in regularly through phone calls and remote environmental monitoring.

Additional Information

This study is being done to learn whether using air cleaners in the home can reduce respiratory symptoms, improve quality of life, and lower the risk of COPD flare-ups and hospitalizations in former smokers.

You may qualify for this study if you meet the following criteria.

Inclusion Criteria:

  • Ages 40+
  • Must be a former smoker, with history of regular cigarette tobacco use
  • Have been told by a physician that you have COPD, chronic bronchitis, emphysema, or chronic cough
  • Ability to lift up to 25 pounds either by self, or with the help of a friend, or relative/family member
  • Not planning to change residence in the next 12 months

Exclusion Criteria:

  • Living in a long-term care facility or a nursing home
  • A condition with less than a year of life expectancy (e.g., metastatic cancer) or in hospice
  • Pregnant

Here’s a step-by-step breakdown:

  1. In-Person Visit: You’ll attend a one-time clinic visit at Johns Hopkins lasting 2–3 hours for screening and enrollment.

  2. Baseline Call: If eligible, you’ll complete a remote phone call to be officially enrolled and randomized.

  3. Air Cleaners Delivered: Two air cleaners will be shipped to your home. You will be required to install and run them for 12 months.

  4. Monitoring Periods: We will ask you to place small air quality testers around your home, and return them to the study after 1 week (up to 3 times).

  5. Follow-Up Calls: You’ll complete 4 scheduled phone check-ins at 3, 6, 9, and 12 months.

  6. Extra Calls if Needed: You may receive additional monthly phone calls about the air cleaners use, as needed.

  7. Year-Long Air Monitoring: Your home will also have continuous monitoring of air quality (PM and NO₂) throughout the study.

Yes! You can receive up to $580 for your time and participation over the course of the 12-month study. You’ll also get to keep 2 working air cleaners with filters at the end of the study. If you need help getting to your screening appointment, a Lyft ride or parking voucher will be provided.

There is no cost for you to participate in our research study.