Memory & Mobility Research Study
Researchers at the Marcus Institute for Aging Research are conducting a study to evaluate the effects of home-based, non-invasive brain stimulation, specifically transcranial direct current stimulation (tDCS), on improving memory, walking, and overall physical functioning in older adults with Motoric Cognitive Risk (MCR).
Fast Facts
Experience Memory Concerns
Slow Walking Speed
Have A Study Partner Who Is Able To Participate
Compensation Provided
Greater Boston, MA Area
Study Background
Home tDCS for MCR
Motoric Cognitive Risk (MCR) is a condition commonly seen in older adults, characterized by slow walking speed and subjective memory concerns, which can significantly affect quality of life. Researchers at the Marcus Institute for Aging Research are conducting a groundbreaking 1-year study to explore innovative solutions for this growing concern. The study aims to evaluate the effects of home-based, non-invasive brain stimulation on improving memory, mobility, and overall physical functioning in individuals with MCR. This research targets a critical aspect of aging by investigating methods to enhance both cognitive and physical health in a safe and accessible manner.
The intervention being studied is transcranial direct current stimulation (tDCS), a non-invasive technology that delivers small electrical currents to the brain through the scalp. Participants will engage in a home-based treatment protocol for 6 and 1/2 month intervention period, administered by a study partner who will receive specialized training. By examining the potential of tDCS to improve memory and walking speed, this study seeks to address the challenges faced by aging individuals with MCR, offering hope for improved independence and quality of life.
Study Background
Home tDCS for MCR
Motoric Cognitive Risk (MCR) is a condition commonly seen in older adults, characterized by slow walking speed and subjective memory concerns, which can significantly affect quality of life. Researchers at the Marcus Institute for Aging Research are conducting a groundbreaking 1-year study to explore innovative solutions for this growing concern. The study aims to evaluate the effects of home-based, non-invasive brain stimulation on improving memory, mobility, and overall physical functioning in individuals with MCR. This research targets a critical aspect of aging by investigating methods to enhance both cognitive and physical health in a safe and accessible manner.
The intervention being studied is transcranial direct current stimulation (tDCS), a non-invasive technology that delivers small electrical currents to the brain through the scalp. Participants will engage in a home-based treatment protocol for 6 and 1/2 month intervention period, administered by a study partner who will receive specialized training. By examining the potential of tDCS to improve memory and walking speed, this study seeks to address the challenges faced by aging individuals with MCR, offering hope for improved independence and quality of life.
Additional Information
This study is being conducted to evaluate the potential of transcranial direct current stimulation (tDCS), a non-invasive and home-based intervention, to improve memory, mobility, and overall physical functioning in older adults with Motoric Cognitive Risk (MCR), a condition linked to aging-related cognitive and physical decline.
You/your loved one may qualify for this study the following criteria are met.
Inclusion Criteria:
- Ages 65-90
- Experience memory concerns without a prior diagnosis of dementia, Alzheimer’s disease, or any other neurodegenerative disorder
- Slow walking speed without reliance on walking assistance devices
- Have a study partner who is also able to participate in study
- Able to undergo MRI scan (no metal in the body, no pacemaker, no claustrophobia)
- No diagnosis of Epilepsy, Traumatic Brain Injury, or Parkinson’s disease
- Have access to the internet
Exclusion Criteria:
- Current diagnosis of cancer (e.g., actively receiving any chemo or radiation therapy)
- Current diagnosis of major psychiatric disorders
If you/your loved one participates in this study, here’s what you can expect:
Study Duration and Visits: Participation will last approximately 12 months, including 10 in-person visits.
Six visits will involve mobility and memory tests along with health questionnaires.
Three visits will include MRI scans.
One visit will require a fasting blood draw.
Home-Based Brain Stimulation:
You will identify a study partner who will administer a daily 45-minute non-invasive brain stimulation (Monday-Friday, between 8 AM-5 PM) for 6 ½ consecutive months.
The study partner will attend the first study visit, where they will receive training on how to administer the stimulation.
At-Home Walking Test:
Once a week, you will complete a 5-minute walking test at home using a smartphone.
By following these steps, you will contribute valuable data to help researchers better understand and develop interventions for Motoric Cognitive Risk (MCR).
As a participant, you can receive up to $720 for participating in this study.
There is no cost for you to participate in our research study.