Psychosis Research Study
Researchers at Columbia University are conducting a study in adults with psychosis or schizophrenia, or who have had experiences seeing visions, hearing voices, or other unusual sensory perceptions, in order to better understand psychosis and the brain.
Fast Facts
Symptoms of Psychosis or Schizophrenia
18-50
Years Old
Compensation
Provided
Conducted in
New York, NY
Study Background
Circuit Computations Underlying Hallucinations
In this study, we are trying to learn more about the symptoms of psychosis, specifically to learn how alterations in the brain may produce certain experiences (including voice hearing or auditory hallucinations) that are common in people with psychosis or schizophrenia. The study involves clinical interviews, computer tests, and magnetic resonance imaging (MRI) scans. It will be conducted at Columbia University Medical Center and Zuckerman Mind Brain Behavior Institute.
Study Background
Circuit Computations Underlying Hallucinations
In this study, we are trying to learn more about the symptoms of psychosis, specifically to learn how alterations in the brain may produce certain experiences (including voice hearing or auditory hallucinations) that are common in people with psychosis or schizophrenia. The study involves clinical interviews, computer tests, and magnetic resonance imaging (MRI) scans. It will be conducted at Columbia University Medical Center and Zuckerman Mind Brain Behavior Institute.
Additional Information
We want to learn how certain brain processes relate to symptoms like hearing voices. By combining interviews, computer tasks, and MRI, we can look for patterns that may explain why these experiences happen and how they differ across people. The goal is to improve scientific understanding and guide future approaches. Insights may point toward more targeted, better-tolerated treatments, but it’s important to note that this is not a treatment study.
You may be eligible for this study if you meet the following criteria.
Inclusion Criteria:
- Ages 18-50
- Diagnosed with or have symptoms of psychosis or schizophrenia, OR
- Have had experiences of hearing voices, seeing visions, or other anomalous sensory experiences
The total time to participate in this study is up to 14 hours. It will involve:
- Screening & baseline assessments (~2-4 hours): Phone/Zoom screening session and a baseline interview (eligibility, brief questionnaires). VIRTUAL
- Computer tasks (up to ~4 hours total): Simple activities like looking at images, listening to sounds, and making quick choices. IN-PERSON
- MRI scans (~2–3 hours depending on breaks): performing the same computer tasks while within the scanner. IN-PERSON
Please note that this study does not involve any medication or treatment.
As a participant, you may receive up to $390 for completing the entire study.
There is no cost for you to participate in our research study.