Alcohol Use Research Study

Researchers at the University of Virginia are conducting a research study in adults to better understand alcohol use and evaluate approaches to help reduce alcohol consumption.

Fast Facts

Adults looking to reduce their alcohol use

Adults

21+

Compensation

provided up to $605

Conducted in

Charlottesville, VA

Study Background

Researchers at the University of Virginia are conducting an alcohol use research study in adults.

Alcohol use disorder can affect craving, decision-making, and daily functioning. Researchers at the University of Virginia are conducting a clinical research study to evaluate the safety, effectiveness, and tolerability of the study medication apremilast in adults who currently drink alcohol and are interested in reducing their alcohol use.

The results of this research may help inform future treatments for alcohol use disorder and improve options for individuals seeking to reduce their drinking. By participating, individuals contribute to advancing alcohol use research and potential treatment approaches.

Study Background

Researchers at the University of Virginia are conducting an alcohol use research study in adults.

Alcohol use disorder can affect craving, decision-making, and daily functioning. Researchers at the University of Virginia are conducting a clinical research study to evaluate the safety, effectiveness, and tolerability of the study medication apremilast in adults who currently drink alcohol and are interested in reducing their alcohol use.

The results of this research may help inform future treatments for alcohol use disorder and improve options for individuals seeking to reduce their drinking. By participating, individuals contribute to advancing alcohol use research and potential treatment approaches.

Additional Information

In this research study, we are seeking to better understand alcohol use and alcohol craving in adults who drink regularly and are interested in reducing their alcohol consumption. We aim to examine how alcohol-related cues influence craving and drinking behavior, and how these processes may be affected by a study medication.

This study evaluates the safety, effectiveness, and tolerability of apremilast at different doses compared to placebo, using laboratory-based assessments, questionnaires, and clinical measures. By studying changes in alcohol craving, consumption patterns, and related behaviors, this research may help inform future treatment approaches for alcohol use disorder.

You may be eligible for this research study if you meet the following criteria:

Inclusion Criteria

  • Drink alcohol regularly
  • Ages 21 and older
  • Interested in reducing alcohol consumption
  • Live within approximately one hour of Charlottesville, VA

The entire study lasts 10 weeks. Once enrolled, the study involves:

In the clinic: 7 in-person visits, including an initial medical screening and weekly visits during the 5-week treatment phase. During these visits, participants will complete assessments of alcohol use, craving, and related behaviors, including questionnaires, laboratory-based tasks, physical exams, ECGs, blood draws, and urine drug screens.

Follow-up: After the treatment phase, participants will complete 1 follow-up visit and 1 follow-up phone call to track progress and ensure safety.

As a participant, you may receive up to $605. 

There is no cost for you to participate in our research study.