High Blood Pressure Research Study
Researchers at Trialmed are conducting a study on a medication for adults with high blood pressure and cardiovascular disease or high cardiovascular risk.
Fast Facts
High Blood Pressure That Is Not Well Controlled
Taking At Least 2 Blood Pressure Medications, Including A Diuretic (Water Pill)
Participants May Be Reimbursed
Conducted In
Evansville, IN
Study Background
This study is evaluating a potential treatment for adults whose high blood pressure is not well controlled.
The research is testing an investigational medication given as an injection under the skin every six months, in addition to participants’ current blood pressure medications. The goal is to determine whether this medication can help reduce the risk of serious cardiovascular events such as heart attack, stroke, heart failure, or cardiovascular death.
This study may be especially relevant for people with a history of cardiovascular disease, including conditions affecting the heart, brain, or circulation.
Study Background
This study is evaluating a new treatment for adults whose high blood pressure is not well controlled.
The research is testing an investigational medication given as an injection under the skin every six months, in addition to participants’ current blood pressure medications. The goal is to determine whether this medication can help reduce the risk of serious cardiovascular events such as heart attack, stroke, heart failure, or cardiovascular death.
This study may be especially relevant for people with a history of cardiovascular disease, including conditions affecting the heart, brain, or circulation.
Additional Information
Researchers want to see if a medication to standard blood pressure treatment can lower the risk of major cardiovascular events while improving overall heart and kidney health.
This study may be especially relevant for individuals with a history of cardiovascular disease (such as heart disease, stroke, or poor circulation). You may be eligible for this study if you meet the following criteria.
Inclusion Criteria:
- High blood pressure that is not well controlled
- Taking at least 2 blood pressure medications, including a diuretic (water pill)
- Not pregnant
- History of heart or blood vessel problems, or considered at high risk for heart disease (e.g., at least 70 or older, diagnosed with diabetes, overweight, smoke cigarettes)
- Not participating in another clinical trial
- No cancer in the past 5 years
Screening: A phone interview to confirm eligibility.
Study Visits: Approximately 10–14 in-person visits over 2.5–5 years at one of seven U.S. sites.
Medication: An injection under the skin every six months (study drug or placebo).
Monitoring: Participants continue their usual blood pressure medications and receive regular health evaluations, lab tests, and cardiovascular monitoring.
7 Site locations:
Evansville, IN; Tucson, AZ; Minneapolis, MN; Melbourne, FL; Birmingham, AL; Phoenix, AZ; San Antonio, TX
There is no cost for you to participate in our research study. Participants may be reimbursed.