OUD & HIV Research Study

Researchers at the University of Miami are conducting a study on how opioid use affects brain health and overall health outcomes in adults who are not living with HIV.

Fast Facts

Adults concerned about their opioid usage

Have used opioids within the past 90 days

Compensation

provided up to $200

Conducted in

Miami, FL

Study Background

Researchers are working to better understand how opioid use may affect the brain, including inflammation, brain function, pain, and fatigue.

Opioids are medications or substances that can affect the brain and body in many ways. While they are sometimes prescribed to treat pain, long-term use may also influence brain health, mood, and physical well-being. Researchers continue to study how ongoing opioid use may impact the brain and other aspects of health.

In this research study at the University of Miami medical campus in Miami, investigators aim to evaluate brain health outcomes in adults who have used opioids for at least the past 90 days. By examining brain imaging, biological markers, and participant experiences, the research team hopes to better understand the relationship between opioid use and factors such as inflammation, pain, fatigue, and cognitive function. Insights from this study may help inform future research and healthcare approaches.

Study Background

Researchers are working to better understand how opioid use may affect the brain, including inflammation, brain function, pain, and fatigue.

Opioids are medications or substances that can affect the brain and body in many ways. While they are sometimes prescribed to treat pain, long-term use may also influence brain health, mood, and physical well-being. Researchers continue to study how ongoing opioid use may impact the brain and other aspects of health.

In this research study at the University of Miami medical campus in Miami, investigators aim to evaluate brain health outcomes in adults who have used opioids for at least the past 90 days. By examining brain imaging, biological markers, and participant experiences, the research team hopes to better understand the relationship between opioid use and factors such as inflammation, pain, fatigue, and cognitive function. Insights from this study may help inform future research and healthcare approaches.

Additional Information

This study is being conducted to better understand how opioid use may affect brain health and related health outcomes, including inflammation, pain, fatigue, and brain function.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

  • Adults concerned about their opioid usage
  • Do not currently have HIV
  • Have used opioids within the past 90 days
  • Live in Florida
  • Not currently pregnant
  • No history of head injuries
  • Able to undergo an MRI (no permanent metal in the body)
  • Ages 18-60

This is a one-visit research study that takes about 5 hours to complete at the University of Miami medical campus in Miami. Participants may complete several procedures during the visit, including:

  1. Screening and questionnaires about health and experiences

  2. Urine sample collection to test for opioid presence

  3. Blood draw to measure biological markers related to inflammation and health

  4. Brain MRI scan to examine brain structure and function

  5. Rapid HIV test (only for participants who have never been tested)

  6. Rapid pregnancy test (for women participants)

If all procedures cannot be completed during the visit, the research team may schedule a follow-up visit or a video meeting to finish the remaining activities.

Participants can receive up to $200 total compensation for completing study procedures:

  • $15 for the blood draw

  • $5 for urine sample collection

  • $30 for completing questionnaires

  • $150 for completing the brain MRI scan

There is no cost for you to participate in our research study.