This study that is funded by National Institute of Health (NIH) is being conducted to better understand why diabetes develops in people with spinal cord injury and how newer medications such as semaglutide help them.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Diagnosed with type 2 diabetes
• Diagnosed with a spinal cord injury
• Ages 18-70
• Not underweight
• Live in Texas
• Not taking medications for weight loss (e.g., Wegovy, Ozempic, or Phentermine)

If you choose to participate, you will:

• Be screened to confirm diagnosis

• Attend in-person visits for testing to measure how your body processes glucose and responds to insulin

• Treated with semaglutide or placebo for 6 months

• Participate in short follow-up visits twice as well as biweekly phone calls

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Yes, participants will be informed about their diabetes status and will receive compensation up to $2100.

There is no cost for you to participate in our research study.