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Bariatric Surgery
Research Study

Researchers at UT Health San Antonio are conducting a study on how the body regulates blood sugar after eating in individuals with and without prior bariatric surgery. This study uses an investigational medication to better understand how insulin and glucagon affect glucose levels. Findings may help improve future treatments for blood sugar control and metabolic health.

Fast Facts

Have had bariatric surgery (gastric bypass (RYGB) or gastric sleeve)

Ages 18-65

Compensation
up to $1,150

Conducted in
San Antonio, TX

Additional Information

Why is this study being done?

This NIH-funded study aims to better understand how the hormone glucagon affects blood sugar control and metabolism in people with or without weight loss surgery. Researchers will examine how insulin and glucagon are released after eating and how these hormones influence blood sugar levels and overall glucose tolerance.

Is this study for me?

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

Ages 18-65
Have had bariatric surgery (gastric bypass (RYGB) or gastric sleeve)
Generally healthy
Do not have diabetes
Not currently pregnant

What will happen if I participate in the study?

All procedures take place at the Texas Diabetes Institute or UT Health Science locations in the San Antonio area. Participants will first complete a screening visit, which includes a glucose tolerance test. If eligible, you will take part in two in-person meal study visits where you will receive either the investigational medication or a placebo, along with continuous glucose monitoring. Each visit lasts about 6–7 hours and is spaced at least two weeks apart. You will also complete follow-up lab testing about 8 weeks after your second visit, along with brief phone check-ins.

Will I be paid for being in this research study?

Yes, participants can receive up to $1,150 for completing the study. Meals will be provided during study visits.

Will it cost me anything to participate in this study?

There is no cost for you to participate in our research study.