This study is being conducted to better understand opioid use disorder and to explore ways to improve cognitive control needed to maintain abstinence.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Ages 18+
• In early abstinence from opioid use
• Receiving buprenorphine (Suboxone) treatment for opioid use disorder

Exclusion Criteria:

• Currently pregnant
• Contraindications to MRI (non-removable metal on or in body, or severe claustrophobia)

To boost your brain, we will ask you to complete 10 brain training sessions in which you practice computer tasks combined with brain stimulation. Brain stimulation is not invasive. It is delivered to your scalp. To see the effects of the intervention, we take pictures of your brain with an MRI, have your do computer tasks, and ask you some questions about substance use.

If you are eligible and decide to participate in the study, you will:

• Have pictures taken of your brain (MRI; 3 sessions)
• Complete brain training sessions (10 days of brain training)
• Complete cognitive control assessments (3 sessions)

Some parts of the study can be completed virtually (e.g. consent, brain training), and some need to be completed in person (e.g. MRI).

Participants can receive up to $465 for their time. Transportation support or reimbursement may also be available.

There is no cost for you to participate in our research study.