Remote Depression In MS
Research Study

NYU Langone Health is studying new ways to treat depression in people with multiple sclerosis (MS). While depression is common in MS and is often treated with medication, not everyone benefits from those options, so more non-drug treatments are needed. This study will test whether at-home noninvasive brain stimulation (tDCS) combined with mindfulness can help reduce depression symptoms in people with MS.

Fast Facts

Diagnosed with multiple sclerosis

Experiencing symptoms of depression (e.g., feeling down or worthless, sleep problems, fatigue)

Compensation
up to $150

Conducted 
remotely

Additional Information

This study is being conducted to better understand depression in people with multiple sclerosis and to explore ways to improve treatment options using non-medication approaches.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

  • Diagnosed with multiple sclerosis (any subtype)
  • Experiencing symptoms of depression
  • Ages 18–65

 

Exclusion Criteria:

  • Recent changes in multiple sclerosis treatment
  • Unstable multiple sclerosis disease (e.g., recent relapse or flare, worsening symptoms)
  • Major or unstable medical or neurological conditions that would interfere with study participation
  •  

Overall Duration
The study lasts about 5.5 months.

At-Home Activities
If eligible, participants will be mailed all study equipment to use at home. They will complete 30 tDCS sessions over 6–8 weeks (Monday through Friday), paired with mindfulness meditation. Each session is done under remote supervision. Participants will also complete follow-up check-ins at 1, 2, and 3 months after treatment. Questionnaires and session data will be collected securely, and no video or audio is recorded without permission.

Participants may receive up to $150 for their time. 

There is no cost for you to participate in our research study.