You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Have a prior diagnosis of kidney stone
• Be currently taking a GLP-1 medication (e.g., Ozempic, Wegovy, Zepbound, Mounjaro)
• Have obesity (BMI ≥ 30)
• Be age 18 or older
• Live in the continental U.S.
• Report difficulty meeting the recommended 2.5 L (84.5 fl oz) urine output daily
• Own a smartphone
• Be willing to participate in a 6-month study with up to 4 Zoom meetings and virtual urine collections

Exclusion Criteria:

• Have a prior diagnosis of a cystine kidney stone
• Have a medical or psychiatric condition or receive treatments that restrict their ability to drink fluids safely or make it difficult to complete the study program
• Have severe obesity BMI > 40

Study Activities and Timeline

The study lasts about 6 months and is completed entirely from home using Zoom, email, phone, text messages, and mailed study materials.

Enrollment and Study Setup

Before enrollment, all participants will complete a baseline 24-hour urine collection.

Participants will then complete one Zoom enrollment session to:

• Learn about hydration and kidney stone prevention
• Review study group assignment and, if assigned to the intervention group, set up the smart water bottle and mobile app
• Measure blood pressure during the session

Participants will also complete a weight measurement after the session.

Study Assessments

Assessments take place at three timepoints: baseline (start of study), month 3, and month 6. Activities include:

• Questionnaires
• Blood pressure and weight measurements
• A 24-hour urine collection using a kit mailed to the participant’s home
  
  • Urine samples are mailed to a laboratory for testing and then destroyed after analysis

Some participants may also be invited to take part in audio-recorded interviews about their study experience at the end of the study.

Daily and Ongoing Activities

Participants will:

• Track thirst levels for 7 days at the beginning of the study through text messages
• Use a smart water bottle and mobile app to monitor daily fluid intake (timing depends on group assignment)
• Receive hourly text reminders to drink water if fluid intake is below goal (for one study group)
• Complete follow-up surveys and repeat measurements at months 3 and 6

All collected information, including fluid intake data, survey responses, and health measurements, will be kept private and used only for research purposes.

Participants may receive up to $150 for completing all study activities. 

There is no cost for you to participate in our research study.